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methyLImp2

This is the development version of methyLImp2; for the stable release version, see methyLImp2.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19

Missing value estimation of DNA methylation data


Bioconductor version: Development (3.24)

This package allows to estimate missing values in DNA methylation data. methyLImp method is based on linear regression since methylation levels show a high degree of inter-sample correlation. Implementation is parallelised over chromosomes since probes on different chromosomes are usually independent. Mini-batch approach to reduce the runtime in case of large number of samples is available.

Author: Pietro Di Lena [aut] ORCID iD ORCID: 0000-0002-1838-8918 , Anna Plaksienko [aut, cre] ORCID iD ORCID: 0000-0001-9607-057X , Claudia Angelini [aut] ORCID iD ORCID: 0000-0001-8350-8464 , Christine Nardini [aut] ORCID iD ORCID: 0000-0001-7601-321X

Maintainer: Anna Plaksienko <anna at plaxienko.com>

Citation (from within R, enter citation("methyLImp2")):

Pietro Di Lena, Anna Plaksienko, Claudia Angelini, Christine Nardini. methyLImp2: Missing value estimation of DNA methylation data. doi:10.18129/B9.bioc.methyLImp2, R package version 1.9.0, https://bioconductor.org/packages/methyLImp2.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("methyLImp2")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("methyLImp2")
methyLImp2 vignette HTML R Script
Reference ManualPDF
NEWSText

Details

biocViews DNAMethylation, MethylationArray, Microarray, Regression, Software
Version1.9.0
In Bioconductor sinceBioC 3.19 (R-4.4) (2.5 years)
License GPL-3
Depends R (>= 4.3.0), ChAMPdata
Imports BiocParallel, parallel, stats, methods, corpcor, SummarizedExperiment, utils
System Requirements
URLhttps://github.com/annaplaksienko/methyLImp2
Bug Reportshttps://github.com/annaplaksienko/methyLImp2/issues
See More
Suggests BiocStyle, knitr, rmarkdown, spelling, testthat (>= 3.0.0)
Linking To
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Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package methyLImp2_1.9.0.tar.gz
Windows Binary (x86_64) methyLImp2_1.9.0.zip
macOS Binary (big-sur-x86_64) methyLImp2_1.9.0.tgz
macOS Binary (sonoma-arm64) methyLImp2_1.9.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/methyLImp2
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/methyLImp2
Package Short Url https://bioconductor.org/packages/methyLImp2/
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