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mbQTL

This is the development version of mbQTL; for the stable release version, see mbQTL.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17

mbQTL: A package for SNP-Taxa mGWAS analysis


Bioconductor version: Development (3.24)

mbQTL is a statistical R package for simultaneous 16srRNA,16srDNA (microbial) and variant, SNP, SNV (host) relationship, correlation, regression studies. We apply linear, logistic and correlation based statistics to identify the relationships of taxa, genus, species and variant, SNP, SNV in the infected host. We produce various statistical significance measures such as P values, FDR, BC and probability estimation to show significance of these relationships. Further we provide various visualization function for ease and clarification of the results of these analysis. The package is compatible with dataframe, MRexperiment and text formats.

Author: Mercedeh Movassagh [aut, cre] ORCID iD ORCID: 0000-0001-7690-0230 , Steven Schiff [aut], Joseph N Paulson [aut]

Maintainer: Mercedeh Movassagh <mercedeh.movassagh at yale.edu>

Citation (from within R, enter citation("mbQTL")):

Mercedeh Movassagh, Steven Schiff, Joseph N Paulson. mbQTL: mbQTL: A package for SNP-Taxa mGWAS analysis. doi:10.18129/B9.bioc.mbQTL, R package version 1.13.0, https://bioconductor.org/packages/mbQTL.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("mbQTL")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("mbQTL")
MbQTL_Vignette HTML R Script
Reference ManualPDF
NEWSText
LICENSEText

Details

biocViews Metagenomics, Microbiome, Regression, SNP, Software, StatisticalMethod, WholeGenome
Version1.13.0
In Bioconductor sinceBioC 3.17 (R-4.3) (3.5 years)
License MIT + file LICENSE
Depends R (>= 4.3.0)
Imports MatrixEQTL, dplyr, ggplot2, readxl, stringr, tidyr, metagenomeSeq, pheatmap, broom, graphics, stats, methods
System Requirements
URL"https://github.com/Mercedeh66/mbQTL"
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package mbQTL_1.13.0.tar.gz
Windows Binary (x86_64) mbQTL_1.13.0.zip
macOS Binary (big-sur-x86_64) mbQTL_1.13.0.tgz
macOS Binary (sonoma-arm64) mbQTL_1.13.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/mbQTL
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/mbQTL
Package Short Url https://bioconductor.org/packages/mbQTL/
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