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magrene

This is the development version of magrene; for the stable release version, see magrene.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16

Motif Analysis In Gene Regulatory Networks


Bioconductor version: Development (3.24)

magrene allows the identification and analysis of graph motifs in (duplicated) gene regulatory networks (GRNs), including lambda, V, PPI V, delta, and bifan motifs. GRNs can be tested for motif enrichment by comparing motif frequencies to a null distribution generated from degree-preserving simulated GRNs. Motif frequencies can be analyzed in the context of gene duplications to explore the impact of small-scale and whole-genome duplications on gene regulatory networks. Finally, users can calculate interaction similarity for gene pairs based on the Sorensen-Dice similarity index.

Author: Fabrício Almeida-Silva [aut, cre] ORCID iD ORCID: 0000-0002-5314-2964 , Yves Van de Peer [aut] ORCID iD ORCID: 0000-0003-4327-3730

Maintainer: Fabrício Almeida-Silva <fabricio_almeidasilva at hotmail.com>

Citation (from within R, enter citation("magrene")):

Fabrício Almeida-Silva, Yves Van de Peer. magrene: Motif Analysis In Gene Regulatory Networks. doi:10.18129/B9.bioc.magrene, R package version 1.15.0, https://bioconductor.org/packages/magrene.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("magrene")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("magrene")
Introduction to magrene HTML R Script
Reference ManualPDF
NEWSText

Details

biocViews GraphAndNetwork, MotifDiscovery, NetworkEnrichment, Software, SystemsBiology
Version1.15.0
In Bioconductor sinceBioC 3.16 (R-4.2) (4 years)
License GPL-3
Depends R (>= 4.2.0)
Imports utils, stats, BiocParallel
System Requirements
URLhttps://github.com/almeidasilvaf/magrene
Bug Reportshttps://support.bioconductor.org/t/magrene
See More
Suggests BiocStyle, covr, knitr, rmarkdown, ggplot2, sessioninfo, testthat (>= 3.0.0)
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Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package magrene_1.15.0.tar.gz
Windows Binary (x86_64) magrene_1.15.0.zip
macOS Binary (big-sur-x86_64) magrene_1.15.0.tgz
macOS Binary (sonoma-arm64) magrene_1.15.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/magrene
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/magrene
Package Short Url https://bioconductor.org/packages/magrene/
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