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hummingbird

This is the development version of hummingbird; for the stable release version, see hummingbird.

All Bioconductor versions of hummingbird

3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14, 3.13, 3.12

Bayesian Hidden Markov Model for the detection of differentially methylated regions

Bioconductor version: 3.24 · Package version: 1.23.0

A package for detecting differential methylation. It exploits a Bayesian hidden Markov model that incorporates location dependence among genomic loci, unlike most existing methods that assume independence among observations. Bayesian priors are applied to permit information sharing across an entire chromosome for improved power of detection. The direct output of our software package is the best sequence of methylation states, eliminating the use of a subjective, and most of the time an arbitrary, threshold of p-value for determining significance. At last, our methodology does not require replication in either or both of the two comparison groups.

Author: Eleni Adam [aut, cre], Tieming Ji [aut], Desh Ranjan [aut]

Maintainer: Eleni Adam <eadam002 at odu.edu>

DOI: 10.18129/B9.bioc.hummingbird

Citation

From within R, enter citation("hummingbird"):

Eleni Adam, Tieming Ji, Desh Ranjan. hummingbird: Bayesian Hidden Markov Model for the detection of differentially methylated regions. doi:10.18129/B9.bioc.hummingbird, R package version 1.23.0, https://bioconductor.org/packages/hummingbird.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("hummingbird")

For older versions of R, please refer to the appropriate Bioconductor release.

Details

Version1.23.0
LicenseGPL (>=2)
Last updated2026-04-28
In Bioconductor sinceBioC 3.12 (R-4.0) (5 years)
Downloads rank1685 of 2,456
Source branchdevel
Build report Bioconductor build system, r-universe
biocViewsBayesian, BiomedicalInformatics, DNAMethylation, DifferentialExpression, DifferentialMethylation, GeneExpression, HiddenMarkovModel, Sequencing, Software
Package Short Url https://bioconductor.org/packages/hummingbird/

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("hummingbird")
The hummingbird HTML R Script
Reference ManualPDF
NEWSText

Download

Follow the installation instructions to use this package in your R session.

Source packagehummingbird_1.23.0.tar.gz
Windows binary (x86_64)hummingbird_1.23.0.zip
macOS binary (arm64)hummingbird_1.23.0.tgz
macOS binary (x86_64)hummingbird_1.23.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/hummingbird
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/hummingbird
Package Downloads ReportDownload Stats
Dependencies

Depends: R (>= 4.0)

Imports: Rcpp, graphics, GenomicRanges, SummarizedExperiment, IRanges

LinkingTo: Rcpp

Suggests: knitr, rmarkdown, BiocStyle