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MutSeqR

This is the development version of MutSeqR; for the stable release version, see MutSeqR.

All Bioconductor versions of MutSeqR

3.24 (devel), 3.23 (release)

Analysis of Error-Corrected Sequencing Data for Mutation Detection

Bioconductor version: 3.24 · Package version: 1.1.0

Standard methods for analysis of mutation data following error- corrected sequencing (ECS) for the purpose of mutagencity assessment. Functions include importing the mutation lists provided by a variant caller, and a set of analytical tools for statistical testing and visualization of mutation data; comparison to COSMIC and/or germline signatures; etc.

Author: Annette E. Dodge [aut] ORCID iD ORCID: 0000-0002-0446-9055 , Andrew Williams [aut] ORCID iD ORCID: 0000-0002-7637-7686 , Danielle P.M. LeBlanc [aut] ORCID iD ORCID: 0000-0002-3847-8371 , David M. Schuster [aut] ORCID iD ORCID: 0009-0001-6316-4358 , Elena Esina [aut] ORCID iD ORCID: 0009-0002-3443-378X , Clint C. Valentine [aut] ORCID iD ORCID: 0000-0001-5630-7368 , Jesse J. Salk [aut] ORCID iD ORCID: 0000-0002-7804-0550 , Alexander Y. Maslov [aut], Christopher Bradley [aut], Carole L. Yauk [aut] ORCID iD ORCID: 0000-0002-6725-3454 , Francesco Marchetti [aut] ORCID iD ORCID: 0000-0002-9435-4867 , Matthew J. Meier [aut, cre] ORCID iD ORCID: 0000-0001-8199-8754 , Geronimo Matteo [ctb] ORCID iD ORCID: 0000-0003-0819-4471 , Health Canada's Genomics Research and Development Initiative [fnd], Canada Research Chairs Program [fnd] (CRC-2020-00060), Burroughs Wellcome Fund [fnd]

Maintainer: Matthew J. Meier <matthew.meier at hc-sc.gc.ca>

DOI: 10.18129/B9.bioc.MutSeqR

Citation

From within R, enter citation("MutSeqR"):

Annette E. Dodge, Andrew Williams, Danielle P.M. LeBlanc, David M. Schuster, Elena Esina, Clint C. Valentine, Jesse J. Salk, Alexander Y. Maslov, Christopher Bradley, Carole L. Yauk, Francesco Marchetti, Matthew J. Meier. MutSeqR: Analysis of Error-Corrected Sequencing Data for Mutation Detection. doi:10.18129/B9.bioc.MutSeqR, R package version 1.1.0, https://bioconductor.org/packages/MutSeqR.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("MutSeqR")

For older versions of R, please refer to the appropriate Bioconductor release.

Details

Version1.1.0
LicenseMIT + file LICENSE
URLhttps://ehsrb-bsrse-bioinformatics.github.io/MutSeqR/
Bug Reportshttps://github.com/EHSRB-BSRSE-Bioinformatics/MutSeqR/issues
Last updated2026-04-28
In Bioconductor sinceBioC 3.23 (R-4.6) (less than a year)
Downloads rank2216 of 2,456
Source branchdevel
Build report Bioconductor build system, r-universe
biocViewsDriverMutation, GeneTarget, GenomicVariation, Sequencing, Software, SomaticMutation, StatisticalMethod, Visualization
Package Short Url https://bioconductor.org/packages/MutSeqR/

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("MutSeqR")
MutSeqR: Error-Corrected Sequencing (ECS) Analysis For Mutagenicity Assessment HTML R Script
Reference ManualPDF
NEWSText

Download

Follow the installation instructions to use this package in your R session.

Source packageMutSeqR_1.1.0.tar.gz
Windows binary (x86_64)MutSeqR_1.1.0.zip
macOS binary (arm64)MutSeqR_1.1.0.tgz
macOS binary (x86_64)MutSeqR_1.1.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/MutSeqR
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/MutSeqR
Package Downloads ReportDownload Stats
Dependencies

Depends: R (>= 4.5.0)

Imports: BiocGenerics, Biostrings, BSgenome, data.table, dplyr, GenomicRanges, ggplot2, here, IRanges, ggdendro, magrittr, methods, plyranges, rlang, S4Vectors, Seqinfo, stats, stringr, SummarizedExperiment, tibble, tidyr, utils, VariantAnnotation

Suggests: binom, BiocManager, BiocStyle, bs4Dash, BSgenome.Hsapiens.UCSC.hg38, BSgenome.Mmusculus.UCSC.mm10, car, colorspace, dendsort, doBy, DT, ExperimentHub, fmsb, fs, ggrepel, gtools, htmltools, httr, knitr, lme4, magick, MutSeqRData, openxlsx, packcircles, patchwork, RColorBrewer, reticulate, rmarkdown, scales, shiny, testthat (>= 3.0.0), trackViewer, withr, yaml, xml2