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MetNet

This is the development version of MetNet; for the stable release version, see MetNet.

All Bioconductor versions of MetNet

3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14, 3.13, 3.12, 3.11, 3.10, 3.9, 3.8

Inferring metabolic networks from untargeted high-resolution mass spectrometry data

Bioconductor version: 3.24 · Package version: 1.31.0

MetNet contains functionality to infer metabolic network topologies from quantitative data and high-resolution mass/charge information. Using statistical models (including correlation, mutual information, regression and Bayes statistics) and quantitative data (intensity values of features) adjacency matrices are inferred that can be combined to a consensus matrix. Mass differences calculated between mass/charge values of features will be matched against a data frame of supplied mass/charge differences referring to transformations of enzymatic activities. In a third step, the two levels of information are combined to form a adjacency matrix inferred from both quantitative and structure information.

Author: Thomas Naake [aut, cre], Liesa Salzer [ctb], Elva Maria Novoa-del-Toro [ctb] ORCID iD ORCID: 0000-0002-6135-5839

Maintainer: Thomas Naake <thomasnaake at googlemail.com>

DOI: 10.18129/B9.bioc.MetNet

Citation

From within R, enter citation("MetNet"):

Thomas Naake. MetNet: Inferring metabolic networks from untargeted high-resolution mass spectrometry data. doi:10.18129/B9.bioc.MetNet, R package version 1.31.0, https://bioconductor.org/packages/MetNet.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("MetNet")

For older versions of R, please refer to the appropriate Bioconductor release.

Details

Version1.31.0
LicenseGPL (>= 3)
Last updated2026-04-28
In Bioconductor sinceBioC 3.8 (R-3.5) (7 years)
Downloads rank735 of 2,456
Source branchdevel
Build report Bioconductor build system, r-universe
biocViewsImmunoOncology, MassSpectrometry, Metabolomics, Network, Regression, Software
Package Short Url https://bioconductor.org/packages/MetNet/

Documentation

Reference ManualPDF
NEWSText

Download

Follow the installation instructions to use this package in your R session.

Source packageMetNet_1.31.0.tar.gz
Windows binary (x86_64)MetNet_1.31.0.zip
macOS binary (arm64)MetNet_1.31.0.tgz
macOS binary (x86_64)MetNet_1.31.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/MetNet
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/MetNet
Package Downloads ReportDownload Stats
Dependencies

Depends: R (>= 4.1), S4Vectors (>= 0.28.1), SummarizedExperiment (>= 1.20.0)

Imports: bnlearn (>= 4.3), BiocParallel (>= 1.12.0), corpcor (>= 1.6.10), dplyr (>= 1.0.3), ggplot2 (>= 3.3.3), GeneNet (>= 1.2.15), GENIE3 (>= 1.7.0), methods (>= 4.1), parmigene (>= 1.0.2), psych (>= 2.1.6), rlang (>= 0.4.10), stabs (>= 0.6), stats (>= 4.1), tibble (>= 3.0.5), tidyr (>= 1.1.2)

Suggests: BiocGenerics (>= 0.24.0), BiocStyle (>= 2.6.1), glmnet (>= 4.1-1), igraph (>= 1.1.2), knitr (>= 1.11), rmarkdown (>= 1.15), testthat (>= 2.2.1), Spectra (>= 1.4.1), MsCoreUtils (>= 1.6.0)