DOI: 10.18129/B9.bioc.HybridMTest  

This is the development version of HybridMTest; for the stable release version, see HybridMTest.

Hybrid Multiple Testing

Bioconductor version: Development (3.19)

Performs hybrid multiple testing that incorporates method selection and assumption evaluations into the analysis using empirical Bayes probability (EBP) estimates obtained by Grenander density estimation. For instance, for 3-group comparison analysis, Hybrid Multiple testing considers EBPs as weighted EBPs between F-test and H-test with EBPs from Shapiro Wilk test of normality as weigth. Instead of just using EBPs from F-test only or using H-test only, this methodology combines both types of EBPs through EBPs from Shapiro Wilk test of normality. This methodology uses then the law of total EBPs.

Author: Stan Pounds <stanley.pounds at stjude.org>, Demba Fofana <demba.fofana at stjude.org>

Maintainer: Demba Fofana <demba.fofana at stjude.org>

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biocViews GeneExpression, Genetics, Microarray, Software
Version 1.47.0
In Bioconductor since BioC 2.10 (R-2.15) (11.5 years)
License GPL Version 2 or later
Depends R (>= 2.9.0), Biobase, fdrtool, MASS, survival
Imports stats
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