Bioconductor 3.23 Release!
Bioc2026 Registration Open!

TSENAT

This is the development version of TSENAT; to use it, please install the devel version of Bioconductor.

Tsallis Entropy Analysis Toolbox


Bioconductor version: Development (3.24)

Quantifies and models isoform-usage complexity in RNA-seq data using Tsallis entropy, a scale-dependent diversity measure. By tuning the entropic index parameter (q), TSENAT examines transcriptome heterogeneity at different scales: rare variants (low q) or dominant isoforms (high q). It enables computing Tsallis entropy and Tsallis divergence from transcript-level estimates, comparing measures between conditions, testing for differences, and visualizing scale-dependent complexity via q-curves.

Author: Cristóbal Gallardo [aut, cre] ORCID iD ORCID: 0000-0002-5752-2155

Maintainer: Cristóbal Gallardo <gallardoalba at pm.me>

Citation (from within R, enter citation("TSENAT")):

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("TSENAT")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("TSENAT")
1. TSENAT: Tsallis Entropy Analysis Toolbox HTML R Script
2. TSENAT Appendix A: Equivalence Validation HTML R Script
3. TSENAT Appendix B: Non-Parametric Validation HTML R Script
Reference Manual PDF
NEWS Text
LICENSE Text

Details

biocViews AlternativeSplicing, DifferentialExpression, DifferentialSplicing, GeneExpression, RNASeq, Software, TranscriptomeVariant, Transcriptomics
Version 0.99.17
In Bioconductor since BioC 3.24 (R-4.6)
License GPL (>= 3) + file LICENSE
Depends R (>= 4.5.0)
Imports SummarizedExperiment, methods, stats, ggplot2, withr, BiocParallel, matrixStats, mgcv, geepack, pheatmap, cowplot, dplyr, tidyr, S4Vectors, rlang, Rcpp, memoise, digest, readr
System Requirements
URL https://gallardoalba.github.io/TSENAT
Bug Reports https://github.com/gallardoalba/TSENAT/issues
See More
Suggests testthat, knitr, rmarkdown, BiocStyle, kableExtra, patchwork, covr, RColorBrewer, gamsel, glmmTMB, glmnet, gridExtra, nlme, fdrtool, MASS, SplicingFactory, devtools, microbenchmark, gtable, e1071
Linking To Rcpp, RcppArmadillo
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package TSENAT_0.99.17.tar.gz
Windows Binary (x86_64)
macOS Binary (big-sur-x86_64) TSENAT_0.99.17.tgz
macOS Binary (sonoma-arm64)
Source Repository git clone https://git.bioconductor.org/packages/TSENAT
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/TSENAT
Bioc Package Browser https://code.bioconductor.org/browse/TSENAT/
Package Short Url https://bioconductor.org/packages/TSENAT/
Package Downloads Report Download Stats