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SpatialArtifacts

This is the released version of SpatialArtifacts; for the devel version, see SpatialArtifacts.

All versions 3.24 (devel), 3.23 (release)

Identification and Classification of Spatial Artifacts in Visium and Visium HD Data


Bioconductor version: Release (3.23)

SpatialArtifacts provides a data-driven two-step workflow to identify, classify, and handle spatial artifacts in spatial transcriptomics data. The package combines median absolute deviation (MAD)-based outlier detection with morphological image processing (fill, outline, and star patterns) to detect edge and interior artifacts. It supports multiple platforms including 10x Genomics Visium (standard and HD), allowing for consistent quality control across different spatial resolutions.

Author: Harriet Jiali He [aut, cre] ORCID iD ORCID: 0009-0003-7827-2735 , Jacqueline R. Thompson [aut], Michael Totty [aut], Stephanie C. Hicks [aut, fnd] ORCID iD ORCID: 0000-0002-7858-0231

Maintainer: Harriet Jiali He <jhe46 at jh.edu>

Citation (from within R, enter citation("SpatialArtifacts")):

Harriet Jiali He, Jacqueline R. Thompson, Michael Totty, Stephanie C. Hicks. SpatialArtifacts: Identification and Classification of Spatial Artifacts in Visium and Visium HD Data. doi:10.18129/B9.bioc.SpatialArtifacts, R package version 1.0.0, https://bioconductor.org/packages/SpatialArtifacts.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("SpatialArtifacts")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("SpatialArtifacts")
SpatialArtifacts Tutorial HTML R Script
Reference ManualPDF
NEWSText

Details

biocViews Classification, DataImport, QualityControl, Software, Spatial, Transcriptomics, WorkflowStep
Version1.0.0
In Bioconductor sinceBioC 3.23 (R-4.6) (< 6 months)
License Artistic-2.0
Depends R (>= 4.4.0)
Imports SpatialExperiment, SummarizedExperiment, S4Vectors, scuttle, dplyr, terra, stats, methods
System Requirementsquarto, GDAL (>= 2.0.1), GEOS (>= 3.4.0), PROJ (>= 4.8.0)
URLhttps://github.com/CambridgeCat13/SpatialArtifacts
Bug Reportshttps://github.com/CambridgeCat13/SpatialArtifacts/issues
See More
Suggests BiocStyle, knitr, rmarkdown, BiocCheck, ggplot2, patchwork, testthat (>= 3.0.0)
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package SpatialArtifacts_1.0.0.tar.gz
Windows Binary (x86_64) SpatialArtifacts_1.0.0.zip (64-bit only)
macOS Binary (big-sur-x86_64) SpatialArtifacts_1.0.0.tgz
macOS Binary (sonoma-arm64) SpatialArtifacts_1.0.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/SpatialArtifacts
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/SpatialArtifacts
Package Short Url https://bioconductor.org/packages/SpatialArtifacts/
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