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SpNeigh

This is the released version of SpNeigh; for the devel version, see SpNeigh.

All versions 3.24 (devel), 3.23 (release)

Spatial Neighborhood Modeling and Differential Expression Analysis for Transcriptomics


Bioconductor version: Release (3.23)

SpNeigh provides methods for neighborhood-aware analysis of spatial transcriptomics data. It supports boundary detection, spatial weighting (centroid- and boundary-based), spatially informed differential expression using spline-based models, and spatial enrichment analysis via the Spatial Enrichment Index (SEI). Designed for compatibility with Seurat objects, SpatialExperiment objects and spatial data frames, SpNeigh enables interpretable, publication-ready analysis of spatial gene expression patterns.

Author: Jinming Cheng [aut, cre] ORCID iD ORCID: 0000-0003-3806-4694

Maintainer: Jinming Cheng <jinming.cheng at outlook.com>

Citation (from within R, enter citation("SpNeigh")):

Jinming Cheng. SpNeigh: Spatial Neighborhood Modeling and Differential Expression Analysis for Transcriptomics. doi:10.18129/B9.bioc.SpNeigh, R package version 1.0.0, https://bioconductor.org/packages/SpNeigh.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("SpNeigh")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("SpNeigh")
Getting Started with SpNeigh HTML R Script
Reference ManualPDF
NEWSText

Details

biocViews DifferentialExpression, GeneExpression, SingleCell, Software, Spatial, Transcriptomics
Version1.0.0
In Bioconductor sinceBioC 3.23 (R-4.6) (< 6 months)
License GPL (>= 3)
Depends R (>= 4.4.0)
Imports concaveman, dbscan, dplyr, FNN, ggplot2, limma, magrittr, Matrix, methods, patchwork, purrr, rlang, scales, Seurat, sf, SingleCellExperiment, SpatialExperiment, splines, stringr, SummarizedExperiment, tibble, tidyr
System Requirements
URLhttps://github.com/jinming-cheng/SpNeigh
Bug Reportshttps://github.com/jinming-cheng/SpNeigh/issues
See More
Suggests BiocStyle, knitr, rmarkdown, SeuratObject, testthat (>= 3.0.0)
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Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package SpNeigh_1.0.0.tar.gz
Windows Binary (x86_64) SpNeigh_1.0.0.zip (64-bit only)
macOS Binary (big-sur-x86_64) SpNeigh_1.0.0.tgz
macOS Binary (sonoma-arm64) SpNeigh_1.0.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/SpNeigh
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/SpNeigh
Package Short Url https://bioconductor.org/packages/SpNeigh/
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