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RBPEqBind

This is the development version of RBPEqBind; to use it, please install the devel version of Bioconductor.

RNA-Binding Protein Competitive Binding Simulation


Bioconductor version: Development (3.24)

Simulates competitive binding of N RBPs to RNA sequences using an equilibrium binding model. Supports single sequences, concentration grids, and transcriptome-wide analysis. Designed for Bioconductor.

Author: Soon Yi [aut, cre] ORCID iD ORCID: 0000-0002-4535-6532 , National Institutes of Health [fnd] (T32 GM152319)

Maintainer: Soon Yi <cu.soonyi at gmail.com>

Citation (from within R, enter citation("RBPEqBind")):
Seminal Bioconductor project articles:

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M (2015). "Orchestrating high-throughput genomic analysis with Bioconductor." Nature Methods, 12(2), 115–121. doi:10.1038/nmeth.3252.

Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JYH, Zhang J (2004). "Bioconductor: open software development for computational biology and bioinformatics." Genome Biology, 5(10), R80. doi:10.1186/gb-2004-5-10-r80.

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("RBPEqBind")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("RBPEqBind")
Introduction to RBPEqBind HTML R Script
Reference Manual PDF

Details

biocViews FunctionalGenomics, GeneRegulation, MathematicalBiology, Software, SystemsBiology, Transcriptomics, Visualization
Version 0.99.4
In Bioconductor since BioC 3.24 (R-4.6)
License GPL-3
Depends R (>= 4.6.0)
Imports Biostrings, data.table, future.apply, GenomicRanges, ggplot2, IRanges, jsonlite, rtracklayer, S4Vectors, stats, SummarizedExperiment, utils
System Requirements
URL https://github.com/S00NYI/RBPEqBind
Bug Reports https://github.com/S00NYI/RBPEqBind/issues
See More
Suggests testthat (>= 3.0.0), knitr, rmarkdown, progressr, BiocStyle, future, vdiffr
Linking To
Enhances
Depends On Me
Imports Me
Suggests Me
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Build Report Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package RBPEqBind_0.99.4.tar.gz
Windows Binary (x86_64)
macOS Binary (big-sur-x86_64) RBPEqBind_0.99.4.tgz
macOS Binary (sonoma-arm64)
Source Repository git clone https://git.bioconductor.org/packages/RBPEqBind
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/RBPEqBind
Bioc Package Browser https://code.bioconductor.org/browse/RBPEqBind/
Package Short Url https://bioconductor.org/packages/RBPEqBind/
Package Downloads Report Download Stats