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PMScanR

This is the released version of PMScanR; for the devel version, see PMScanR.

Protein motifs analysis and visualisation


Bioconductor version: Release (3.23)

Provides tools for large-scale protein motif analysis and visualization in R. PMScanR facilitates the identification of motifs using external tools like PROSITE's ps_scan (handling necessary file downloads and execution) and enables downstream analysis of results. Key features include parsing scan outputs, converting formats (e.g., to GFF-like structures), generating motif occurrence matrices, and creating informative visualizations such as heatmaps, sequence logos (via seqLogo/ggseqlogo). The package also offers an optional Shiny-based graphical user interface for interactive analysis, aiming to streamline the process of exploring motif patterns across multiple protein sequences.

Author: Jan Pawel Jastrzebski [aut, cre] ORCID iD ORCID: 0000-0001-8699-7742 , Monika Gawronska [ctb] ORCID iD ORCID: 0009-0001-2677-6371 , Wiktor Babis [ctb] ORCID iD ORCID: 0009-0006-3648-3413 , Miriana Quaranta [ctb] ORCID iD ORCID: 0009-0003-0855-485X , Damian Czopek [ctb, aut] ORCID iD ORCID: 0009-0005-3471-4866

Maintainer: Jan Pawel Jastrzebski <bioinformatyka at gmail.com>

Citation (from within R, enter citation("PMScanR")):
Seminal Bioconductor project articles:

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M (2015). "Orchestrating high-throughput genomic analysis with Bioconductor." Nature Methods, 12(2), 115–121. doi:10.1038/nmeth.3252.

Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JYH, Zhang J (2004). "Bioconductor: open software development for computational biology and bioinformatics." Genome Biology, 5(10), R80. doi:10.1186/gb-2004-5-10-r80.

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("PMScanR")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("PMScanR")
PMScanR: Protein Motif Scanning and Analysis HTML R Script
Reference Manual PDF
NEWS Text

Details

biocViews MotifDiscovery, Software, Visualization
Version 1.2.0
In Bioconductor since BioC 3.22 (R-4.5) (1 year)
License GPL-3
Depends
Imports dplyr (>= 1.1.0), shiny, bslib, shinyFiles, plotly, rtracklayer, reshape2, ggseqlogo, ggplot2, seqinr, magrittr, rlang, utils, stringr, BiocFileCache
System Requirements Perl
URL https://github.com/prodakt/PMScanR
Bug Reports https://github.com/prodakt/PMScanR/issues
See More
Suggests BiocStyle, knitr, seqLogo, rmarkdown, testthat (>= 3.0.0)
Linking To
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package PMScanR_1.2.0.tar.gz
Windows Binary (x86_64) PMScanR_1.2.0.zip
macOS Binary (big-sur-x86_64) PMScanR_1.2.0.tgz
macOS Binary (sonoma-arm64) PMScanR_1.2.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/PMScanR
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/PMScanR
Bioc Package Browser https://code.bioconductor.org/browse/PMScanR/
Package Short Url https://bioconductor.org/packages/PMScanR/
Package Downloads Report Download Stats