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MutSeqR

Analysis of Error-Corrected Sequencing Data for Mutation Detection

Bioconductor version: 3.23 · Package version: 1.0.0

Other Bioconductor versions

devel is the development version; release is the current stable one.

3.24 (devel), 3.23 (release)

Standard methods for analysis of mutation data following error- corrected sequencing (ECS) for the purpose of mutagencity assessment. Functions include importing the mutation lists provided by a variant caller, and a set of analytical tools for statistical testing and visualization of mutation data; comparison to COSMIC and/or germline signatures; etc.

DOI: 10.18129/B9.bioc.MutSeqR

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("MutSeqR")

Details

MaintainerMatthew J. Meier <matthew.meier@hc-sc.gc.ca>
AuthorAnnette E. Dodge [aut] (ORCID: <https://orcid.org/0000-0002-0446-9055>), Andrew Williams [aut] (ORCID: <https://orcid.org/0000-0002-7637-7686>), Danielle P.M. LeBlanc [aut] (ORCID: <https://orcid.org/0000-0002-3847-8371>), David M. Schuster [aut] (ORCID: <https://orcid.org/0009-0001-6316-4358>), Elena Esina [aut] (ORCID: <https://orcid.org/0009-0002-3443-378X>), Clint C. Valentine [aut] (ORCID: <https://orcid.org/0000-0001-5630-7368>), Jesse J. Salk [aut] (ORCID: <https://orcid.org/0000-0002-7804-0550>), Alexander Y. Maslov [aut], Christopher Bradley [aut], Carole L. Yauk [aut] (ORCID: <https://orcid.org/0000-0002-6725-3454>), Francesco Marchetti [aut] (ORCID: <https://orcid.org/0000-0002-9435-4867>), Matthew J. Meier [aut, cre] (ORCID: <https://orcid.org/0000-0001-8199-8754>), Geronimo Matteo [ctb] (ORCID: <https://orcid.org/0000-0003-0819-4471>), Health Canada's Genomics Research and Development Initiative [fnd], Canada Research Chairs Program [fnd] (CRC-2020-00060), Burroughs Wellcome Fund [fnd]
LicenseMIT + file LICENSE
URLhttps://ehsrb-bsrse-bioinformatics.github.io/MutSeqR/
Bug Reportshttps://github.com/EHSRB-BSRSE-Bioinformatics/MutSeqR/issues
Source branchRELEASE_3_23
Build report Bioconductor build system, r-universe
biocViewsDriverMutation, GeneTarget, GenomicVariation, Sequencing, Software, SomaticMutation, StatisticalMethod, Visualization
Package Short Url https://bioconductor.org/packages/MutSeqR/

Citation

From within R, enter citation("MutSeqR"):

Annette E. Dodge, Andrew Williams, Danielle P.M. LeBlanc, David M. Schuster, Elena Esina, Clint C. Valentine, Jesse J. Salk, Alexander Y. Maslov, Christopher Bradley, Carole L. Yauk, Francesco Marchetti, Matthew J. Meier. MutSeqR: Analysis of Error-Corrected Sequencing Data for Mutation Detection. doi:10.18129/B9.bioc.MutSeqR, R package version 1.0.0, https://bioconductor.org/packages/MutSeqR.

Generated from the package metadata; it may differ from the package's own citation.

Download

Follow the installation instructions to use this package in your R session.

Source packageMutSeqR_1.0.0.tar.gz
Windows binary (x86_64)MutSeqR_1.0.0.zip
macOS binary (arm64)MutSeqR_1.0.0.tgz
macOS binary (x86_64)MutSeqR_1.0.0.tgz
Dependencies

Depends: R (>= 4.5.0)

Imports: BiocGenerics, Biostrings, BSgenome, data.table, dplyr, GenomicRanges, ggplot2, here, IRanges, ggdendro, magrittr, methods, plyranges, rlang, S4Vectors, Seqinfo, stats, stringr, SummarizedExperiment, tibble, tidyr, utils, VariantAnnotation

Suggests: binom, BiocManager, BiocStyle, bs4Dash, BSgenome.Hsapiens.UCSC.hg38, BSgenome.Mmusculus.UCSC.mm10, car, colorspace, dendsort, doBy, DT, ExperimentHub, fmsb, fs, ggrepel, gtools, htmltools, httr, knitr, lme4, magick, MutSeqRData, openxlsx, packcircles, patchwork, RColorBrewer, reticulate, rmarkdown, scales, shiny, testthat (>= 3.0.0), trackViewer, withr, yaml, xml2