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MIRit

This is the released version of MIRit; for the devel version, see MIRit.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19

Integrate microRNA and gene expression to decipher pathway complexity


Bioconductor version: Release (3.23)

MIRit is an R package that provides several methods for investigating the relationships between miRNAs and genes in different biological conditions. In particular, MIRit allows to explore the functions of dysregulated miRNAs, and makes it possible to identify miRNA-gene regulatory axes that control biological pathways, thus enabling the users to unveil the complexity of miRNA biology. MIRit is an all-in-one framework that aims to help researchers in all the central aspects of an integrative miRNA-mRNA analyses, from differential expression analysis to network characterization.

Author: Jacopo Ronchi [aut, cre] ORCID iD ORCID: 0000-0001-5520-4631 , Maria Foti [fnd] ORCID iD ORCID: 0000-0002-4481-1900

Maintainer: Jacopo Ronchi <jacopo.ronchi at unimib.it>

Citation (from within R, enter citation("MIRit")):

Jacopo Ronchi. MIRit: Integrate microRNA and gene expression to decipher pathway complexity. doi:10.18129/B9.bioc.MIRit, R package version 1.8.0, https://bioconductor.org/packages/MIRit.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("MIRit")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("MIRit")
Integrate miRNA and gene expression data with MIRit HTML R Script
Reference ManualPDF
NEWSText

Details

biocViews DifferentialExpression, Epigenetics, FunctionalGenomics, GeneExpression, GeneRegulation, Network, NetworkEnrichment, NetworkInference, Pathways, Software, SystemsBiology
Version1.8.0
In Bioconductor sinceBioC 3.19 (R-4.4) (2.5 years)
License GPL (>= 3)
Depends MultiAssayExperiment, R (>= 4.4.0)
Imports AnnotationDbi, BiocFileCache, BiocParallel, DESeq2, edgeR, fgsea, genekitr, geneset, ggplot2, ggpubr, graph, graphics, graphite, grDevices, httr, limma, methods, Rcpp, Rgraphviz (>= 2.44.0), rlang, stats, utils
System Requirements
URLhttps://jacopo-ronchi.github.io/MIRit/ https://github.com/jacopo-ronchi/MIRit
Bug Reportshttps://github.com/jacopo-ronchi/MIRit/issues
See More
Suggests BiocStyle, biomaRt, BSgenome.Hsapiens.UCSC.hg38, GenomicRanges, ggrepel, ggridges, Gviz, gwasrapidd, knitr, MonoPoly, org.Hs.eg.db, rmarkdown, testthat (>= 3.0.0)
Linking To Rcpp
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package MIRit_1.8.0.tar.gz
Windows Binary (x86_64)
macOS Binary (big-sur-x86_64) MIRit_1.8.0.tgz
macOS Binary (sonoma-arm64) MIRit_1.8.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/MIRit
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/MIRit
Package Short Url https://bioconductor.org/packages/MIRit/
Package Downloads ReportDownload Stats