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LIPIDIFy

This is the development version of LIPIDIFy; to use it, please install the devel version of Bioconductor.

Comprehensive Lipidomics Data Analysis with Interactive Visualization


Bioconductor version: Development (3.24)

Provides a comprehensive toolkit for end-to-end lipidomics data analysis, including missing value imputation, batch effect correction, normalization, differential abundance analysis using limma and edgeR, gene set enrichment analysis, and extensive visualization capabilities. Lipid names are automatically classified by class, subclass, and fatty-acid saturation. Features both an interactive Shiny interface for bench biologists and fully scriptable R functions for bioinformaticians. Supports flexible custom lipid classification schemes and user-defined enrichment sets.

Author: Fayrouz Hammal [aut, cre] ORCID iD ORCID: 0000-0002-7612-4953 , Karen Sheppard [fnd] (NHMRC of Australia grant #2020050)

Maintainer: Fayrouz Hammal <fayrouz.hammal at petermac.org>

Citation (from within R, enter citation("LIPIDIFy")):
Seminal Bioconductor project articles:

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M (2015). "Orchestrating high-throughput genomic analysis with Bioconductor." Nature Methods, 12(2), 115–121. doi:10.1038/nmeth.3252.

Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JYH, Zhang J (2004). "Bioconductor: open software development for computational biology and bioinformatics." Genome Biology, 5(10), R80. doi:10.1186/gb-2004-5-10-r80.

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("LIPIDIFy")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("LIPIDIFy")
LIPIDIFy HTML R Script
Reference Manual PDF

Details

biocViews BatchEffect, Classification, DataImport, DifferentialExpression, GeneSetEnrichment, Lipidomics, MassSpectrometry, MultipleComparison, Normalization, Preprocessing, QualityControl, ShinyApps, Software, Visualization
Version 0.99.7
In Bioconductor since BioC 3.24 (R-4.6)
License MIT + file LICENSE
Depends R (>= 4.5.0)
Imports shiny (>= 1.8.0), shinydashboard, ggplot2 (>= 3.5.0), ggrepel, plotly, DT, tidyr, dplyr, scales, gridExtra, grid, pheatmap, limma, edgeR, fgsea, FactoMineR, pls, openxlsx, rmarkdown, stringr, withr, utils, stats, grDevices
System Requirements
URL https://github.com/fayrouzhammal/LIPIDIFy
Bug Reports https://github.com/fayrouzhammal/LIPIDIFy/issues
See More
Suggests BiocStyle, knitr, testthat (>= 3.0.0), impute, sva, vsn, SummarizedExperiment, tinytex, shinytest2, chromote
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package LIPIDIFy_0.99.7.tar.gz
Windows Binary (x86_64)
macOS Binary (big-sur-x86_64) LIPIDIFy_0.99.7.tgz
macOS Binary (sonoma-arm64)
Source Repository git clone https://git.bioconductor.org/packages/LIPIDIFy
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/LIPIDIFy
Bioc Package Browser https://code.bioconductor.org/browse/LIPIDIFy/
Package Short Url https://bioconductor.org/packages/LIPIDIFy/
Package Downloads Report Download Stats