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GBScleanR

This is the released version of GBScleanR; for the devel version, see GBScleanR.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15

Error correction tool for noisy genotyping by sequencing (GBS) data


Bioconductor version: Release (3.23)

GBScleanR is a package for quality check, filtering, and error correction of genotype data derived from next generation sequcener (NGS) based genotyping platforms. GBScleanR takes Variant Call Format (VCF) file as input. The main function of this package is `estGeno()` which estimates the true genotypes of samples from given read counts for genotype markers using a hidden Markov model with incorporating uneven observation ratio of allelic reads. This implementation gives robust genotype estimation even in noisy genotype data usually observed in Genotyping-By-Sequnencing (GBS) and similar methods, e.g. RADseq. The current implementation accepts genotype data of a diploid population at any generation of multi-parental cross, e.g. biparental F2 from inbred parents, biparental F2 from outbred parents, and 8-way recombinant inbred lines (8-way RILs) which can be refered to as MAGIC population.

Author: Tomoyuki Furuta [aut, cre] ORCID iD ORCID: 0000-0002-0869-6626

Maintainer: Tomoyuki Furuta <f.tomoyuki at okayama-u.ac.jp>

Citation (from within R, enter citation("GBScleanR")):

Tomoyuki Furuta. GBScleanR: Error correction tool for noisy genotyping by sequencing (GBS) data. doi:10.18129/B9.bioc.GBScleanR, R package version 2.6.1, https://bioconductor.org/packages/GBScleanR.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("GBScleanR")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("GBScleanR")
BasicUsageOfGBScleanR.html HTML R Script
Reference ManualPDF
NEWSText
LICENSEText

Details

biocViews GeneticVariability, Genetics, HiddenMarkovModel, QualityControl, SNP, Sequencing, Software
Version2.6.1
In Bioconductor sinceBioC 3.15 (R-4.2) (4.5 years)
License GPL-3 + file LICENSE
Depends SeqArray
Imports stats, utils, methods, ggplot2, tidyr, expm, Rcpp, RcppParallel, gdsfmt
System RequirementsGNU make, C++11
URLhttps://github.com/tomoyukif/GBScleanR
Bug Reportshttps://github.com/tomoyukif/GBScleanR/issues
See More
Suggests BiocStyle, testthat (>= 3.0.0), knitr, rmarkdown
Linking To Rcpp, RcppParallel
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package GBScleanR_2.6.1.tar.gz
Windows Binary (x86_64) GBScleanR_2.6.1.zip
macOS Binary (big-sur-x86_64) GBScleanR_2.6.1.tgz
macOS Binary (sonoma-arm64) GBScleanR_2.6.1.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/GBScleanR
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/GBScleanR
Package Short Url https://bioconductor.org/packages/GBScleanR/
Package Downloads ReportDownload Stats
Old Source Packages for BioC 3.23Source Archive