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EpiDISH

This is the released version of EpiDISH; for the devel version, see EpiDISH.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14, 3.13, 3.12, 3.11, 3.10, 3.9, 3.8, 3.7, 3.6

Epigenetic Dissection of Intra-Sample-Heterogeneity


Bioconductor version: Release (3.23)

EpiDISH is a R package to infer the proportions of a priori known cell-types present in a sample representing a mixture of such cell-types. Right now, the package can be used on DNAm data of blood-tissue of any age, from birth to old-age, generic epithelial tissue and breast tissue. Besides, the package provides a function that allows the identification of differentially methylated cell-types and their directionality of change in Epigenome-Wide Association Studies.

Author: Andrew E. Teschendorff [aut], Shijie C. Zheng [aut, cre]

Maintainer: Shijie C. Zheng <shijieczheng at gmail.com>

Citation (from within R, enter citation("EpiDISH")):

Andrew E. Teschendorff, Shijie C. Zheng. EpiDISH: Epigenetic Dissection of Intra-Sample-Heterogeneity. doi:10.18129/B9.bioc.EpiDISH, R package version 2.28.0, https://bioconductor.org/packages/EpiDISH.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("EpiDISH")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("EpiDISH")
Epigenetic Dissection of Intra-Sample-Heterogeneity HTML R Script
Reference ManualPDF
NEWSText

Details

biocViews DNAMethylation, DifferentialMethylation, Epigenetics, ImmunoOncology, MethylationArray, Software
Version2.28.0
In Bioconductor sinceBioC 3.6 (R-3.4) (9 years)
License GPL-2
Depends R (>= 4.1)
Imports MASS, e1071, quadprog, parallel, stats, matrixStats, stringr, locfdr, Matrix, genefilter
System Requirements
URLhttps://github.com/sjczheng/EpiDISH
Bug Reportshttps://github.com/sjczheng/EpiDISH/issues
See More
Suggests roxygen2, GEOquery, BiocStyle, knitr, rmarkdown, Biobase, testthat
Linking To
Enhances
Depends On Me TOAST
Imports Me
Suggests Me CimpleG, FlowSorted.Blood.EPIC, planet
Links To Me
Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package EpiDISH_2.28.0.tar.gz
Windows Binary (x86_64) EpiDISH_2.28.0.zip
macOS Binary (big-sur-x86_64) EpiDISH_2.28.0.tgz
macOS Binary (sonoma-arm64) EpiDISH_2.28.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/EpiDISH
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/EpiDISH
Package Short Url https://bioconductor.org/packages/EpiDISH/
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