DOI: 10.18129/B9.bioc.pRoloc    

A unifying bioinformatics framework for spatial proteomics

Bioconductor version: Release (3.6)

The pRoloc package implements machine learning and visualisation methods for the analysis and interogation of quantitiative mass spectrometry data to reliably infer protein sub-cellular localisation.

Author: Laurent Gatto and Lisa M. Breckels with contributions from Thomas Burger and Samuel Wieczorek

Maintainer: Laurent Gatto <lg390 at>

Citation (from within R, enter citation("pRoloc")):


To install this package, start R and enter:

## try http:// if https:// URLs are not supported


HTML R Script A transfer learning algorithm for spatial proteomics
HTML R Script Annotating spatial proteomics data
HTML R Script Machine learning techniques available in pRoloc
HTML R Script Using pRoloc for spatial proteomics data analysis
PDF   Reference Manual
Text   NEWS
Video   pRoloc, pRolocdata and pRolocGUI


biocViews Classification, Clustering, MassSpectrometry, Proteomics, QualityControl, Software
Version 1.18.0
In Bioconductor since BioC 2.12 (R-3.0) (5 years)
License GPL-2
Depends R (>= 2.15), MSnbase(>= 1.19.20), MLInterfaces(>= 1.37.1), methods, Rcpp (>= 0.10.3), BiocParallel
Imports Biobase, mclust (>= 4.3), caret, e1071, sampling, class, kernlab, Rtsne (>= 0.13), lattice, nnet, randomForest, proxy, FNN, hexbin, BiocGenerics, stats, dendextend, RColorBrewer, scales, MASS, knitr, mvtnorm, gtools, plyr, ggplot2, biomaRt, utils, grDevices, graphics
LinkingTo Rcpp, RcppArmadillo
Suggests testthat, rmarkdown, pRolocdata(>= 1.9.4), roxygen2, synapter, xtable, rgl, BiocStyle(>= 2.5.19), hpar(>= 1.15.3), dplyr, GO.db, AnnotationDbi
Depends On Me pRolocGUI
Imports Me
Suggests Me MSnbase, pRolocdata, RforProteomics
Build Report  

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package pRoloc_1.18.0.tar.gz
Windows Binary (32- & 64-bit)
Mac OS X 10.11 (El Capitan) pRoloc_1.18.0.tgz
Source Repository git clone
Package Short Url
Package Downloads Report Download Stats

Documentation »


R / CRAN packages and documentation

Support »

Please read the posting guide. Post questions about Bioconductor to one of the following locations: