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wavFeatExt

This is the released version of wavFeatExt; for the devel version, see wavFeatExt.

Wavelet-based Feature Extraction for Copy-number Alteration Data


Bioconductor version: Release (3.23)

Provides tools for simulating copy-number alteration (CNA) profiles, applying a non-decimated Haar wavelet transform to genomic signals, and extracting wavelet-derived features for use in supervised learning. Multiple machine learning methods including lasso and elastic-net regularisation, random forest, partial least squares, neural networks and k-nearest neighbours are implemented to train predictive models from genomic feature vectors. The workflow enables end-to-end analysis from CNA simulation to feature extraction and classification.

Author: Maharani Ahsani Ummi [aut, cre], Arief Gusnanto [aut]

Maintainer: Maharani Ahsani Ummi <maharaniahsani at itb.ac.id>

Citation (from within R, enter citation("wavFeatExt")):
Seminal Bioconductor project articles:

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M (2015). "Orchestrating high-throughput genomic analysis with Bioconductor." Nature Methods, 12(2), 115–121. doi:10.1038/nmeth.3252.

Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JYH, Zhang J (2004). "Bioconductor: open software development for computational biology and bioinformatics." Genome Biology, 5(10), R80. doi:10.1186/gb-2004-5-10-r80.

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("wavFeatExt")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("wavFeatExt")
Introduction to wavFeatExt HTML R Script
Reference Manual PDF
NEWS Text

Details

biocViews Classification, CopyNumberVariation, FeatureExtraction, GenomicVariation, Software
Version 1.0.0
In Bioconductor since BioC 3.23 (R-4.6) (< 6 months)
License GPL-3
Depends R (>= 4.6)
Imports DNAcopy, wavethresh, MASS, randomForest, glmnet, pROC, neuralnet, e1071, class, caret, ica, stats, graphics, utils, pls, matrixStats
System Requirements
URL https://github.com/maharaniau/wavFeatExt
Bug Reports https://github.com/maharaniau/wavFeatExt/issues
See More
Suggests BiocStyle, knitr, rmarkdown, testthat (>= 3.0.0)
Linking To
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package wavFeatExt_1.0.0.tar.gz
Windows Binary (x86_64) wavFeatExt_1.0.0.zip
macOS Binary (big-sur-x86_64) wavFeatExt_1.0.0.tgz
macOS Binary (sonoma-arm64) wavFeatExt_1.0.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/wavFeatExt
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/wavFeatExt
Bioc Package Browser https://code.bioconductor.org/browse/wavFeatExt/
Package Short Url https://bioconductor.org/packages/wavFeatExt/
Package Downloads Report Download Stats