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MPO.db

A set of annotation maps describing the Mouse Phenotype Ontology


Bioconductor version: Release (3.18)

We have developed the human disease ontology R package HDO.db, which provides the semantic relationship between human diseases. Relying on the DOSE and GOSemSim packages we developed, we can carry out disease enrichment and semantic similarity analyses. Many biological studies are achieved through mouse models, and a large number of data indicate the association between genotypes and phenotypes or diseases. The study of model organisms can be transformed into useful knowledge about normal human biology and disease to facilitate treatment and early screening for diseases. Organism-specific genotype-phenotypic associations can be applied to cross-species phenotypic studies to clarify previously unknown phenotypic connections in other species. Using the same principle to diseases can identify genetic associations and even help to identify disease associations that are not obvious. Therefore, as a supplement to HDO.db and DOSE, we developed mouse phenotypic ontology R package MPO.db.

Author: Erqiang Hu [aut, cre]

Maintainer: Erqiang Hu <13766876214 at 163.com>

Citation (from within R, enter citation("MPO.db")):

Installation

To install this package, start R (version "4.3") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("MPO.db")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("MPO.db")
MPO_vignette HTML R Script
Reference Manual PDF
NEWS Text

Details

biocViews AnnotationData, AnnotationHub, FunctionalAnnotation
Version 0.99.7
License Artistic-2.0
Depends R (>= 4.3.0)
Imports AnnotationDbi, AnnotationHub, BiocFileCache, DBI, methods, utils
System Requirements
URL https://github.com/YuLab-SMU/MPO.db
Bug Reports https://github.com/YuLab-SMU/MPO.db/issues
See More
Suggests rmarkdown, knitr, testthat (>= 3.0.0)
Linking To
Enhances
Depends On Me
Imports Me
Suggests Me DOSE
Links To Me

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package MPO.db_0.99.7.tar.gz
Windows Binary
macOS Binary (x86_64)
macOS Binary (arm64)
Package Short Url https://bioconductor.org/packages/MPO.db/
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