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vulcan

This is the released version of vulcan; for the devel version, see vulcan.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14, 3.13, 3.12, 3.11, 3.10, 3.9, 3.8, 3.7, 3.6

VirtUaL ChIP-Seq data Analysis using Networks


Bioconductor version: Release (3.23)

Vulcan (VirtUaL ChIP-Seq Analysis through Networks) is a package that interrogates gene regulatory networks to infer cofactors significantly enriched in a differential binding signature coming from ChIP-Seq data. In order to do so, our package combines strategies from different BioConductor packages: DESeq for data normalization, ChIPpeakAnno and DiffBind for annotation and definition of ChIP-Seq genomic peaks, csaw to define optimal peak width and viper for applying a regulatory network over a differential binding signature.

Author: Federico M. Giorgi, Andrew N. Holding, Florian Markowetz

Maintainer: Federico M. Giorgi <federico.giorgi at gmail.com>

Citation (from within R, enter citation("vulcan")):

Federico M. Giorgi, Andrew N. Holding, Florian Markowetz. vulcan: VirtUaL ChIP-Seq data Analysis using Networks. doi:10.18129/B9.bioc.vulcan, R package version 1.34.0, https://bioconductor.org/packages/vulcan.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("vulcan")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("vulcan")
Vulcan: VirtUaL ChIP-Seq Analysis through Networks PDF R Script
Reference ManualPDF
NEWSText

Details

biocViews ChIPSeq, GeneExpression, NetworkEnrichment, Software, SystemsBiology
Version1.34.0
In Bioconductor sinceBioC 3.6 (R-3.4) (9 years)
License LGPL-3
Depends R (>= 4.0), ChIPpeakAnno, TxDb.Hsapiens.UCSC.hg19.knownGene, zoo, GenomicRanges, S4Vectors, viper, DiffBind, locfit
Imports wordcloud, csaw, gplots, stats, utils, caTools, graphics, DESeq2, Biobase
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package vulcan_1.34.0.tar.gz
Windows Binary (x86_64) vulcan_1.34.0.zip
macOS Binary (big-sur-x86_64) vulcan_1.34.0.tgz
macOS Binary (sonoma-arm64) vulcan_1.34.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/vulcan
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/vulcan
Package Short Url https://bioconductor.org/packages/vulcan/
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