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ramr

This is the released version of ramr; for the devel version, see ramr.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14, 3.13

Detection of Rare Aberrantly Methylated Regions in Array and NGS Data


Bioconductor version: Release (3.23)

ramr is an R package for detection of epimutations (i.e., infrequent aberrant DNA methylation events) in large data sets obtained by methylation profiling using array or high-throughput methylation sequencing. In addition, package provides functions to visualize found aberrantly methylated regions (AMRs), to generate sets of all possible regions to be used as reference sets for enrichment analysis, and to generate biologically relevant test data sets for performance evaluation of AMR/DMR search algorithms.

Author: Oleksii Nikolaienko [aut, cre] ORCID iD ORCID: 0000-0002-5910-4934

Maintainer: Oleksii Nikolaienko <oleksii.nikolaienko at gmail.com>

Citation (from within R, enter citation("ramr")):

Oleksii Nikolaienko. ramr: Detection of Rare Aberrantly Methylated Regions in Array and NGS Data. doi:10.18129/B9.bioc.ramr, R package version 1.20.2, https://bioconductor.org/packages/ramr.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("ramr")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("ramr")
ramr HTML R Script
Reference ManualPDF
NEWSText

Details

biocViews DNAMethylation, DifferentialMethylation, Epigenetics, MethylSeq, MethylationArray, Software
Version1.20.2
In Bioconductor sinceBioC 3.13 (R-4.1) (5.5 years)
License Artistic-2.0
Depends R (>= 4.1)
Imports methods, data.table, Seqinfo, GenomicRanges, IRanges, BiocGenerics, S4Vectors, Rcpp
System RequirementsC++20, GNU make
URLhttps://github.com/BBCG/ramr
Bug Reportshttps://github.com/BBCG/ramr/issues
See More
Suggests RUnit, knitr, rmarkdown, ggplot2, gridExtra, annotatr, LOLA, org.Hs.eg.db, TxDb.Hsapiens.UCSC.hg19.knownGene, parallel, doParallel, foreach, doRNG, matrixStats, EnvStats, ExtDist, gamlss, gamlss.dist
Linking To Rcpp
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package ramr_1.20.2.tar.gz
Windows Binary (x86_64) ramr_1.20.2.zip
macOS Binary (big-sur-x86_64) ramr_1.20.2.tgz
macOS Binary (sonoma-arm64) ramr_1.20.2.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/ramr
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/ramr
Package Short Url https://bioconductor.org/packages/ramr/
Package Downloads ReportDownload Stats
Old Source Packages for BioC 3.23Source Archive