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maaslin3

"Refining and extending generalized multivariate linear models for meta-omic association discovery"

Bioconductor version: 3.23 · Package version: 1.4.0

Other Bioconductor versions

devel is the development version; release is the current stable one.

3.24 (devel), 3.23 (release)

MaAsLin 3 refines and extends generalized multivariate linear models for meta-omicron association discovery. It finds abundance and prevalence associations between microbiome meta-omics features and complex metadata in population-scale epidemiological studies. The software includes multiple analysis methods (including support for multiple covariates, repeated measures, and ordered predictors), filtering, normalization, and transform options to customize analysis for your specific study.

DOI: 10.18129/B9.bioc.maaslin3

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("maaslin3")

Details

MaintainerWilliam Nickols <willnickols@g.harvard.edu>
AuthorWilliam Nickols [aut, cre] (ORCID: <https://orcid.org/0000-0001-8214-9746>), Jacob Nearing [aut]
LicenseMIT + file LICENSE
URLhttp://huttenhower.sph.harvard.edu/maaslin3
Bug Reportshttps://github.com/biobakery/maaslin3/issues
Source branchRELEASE_3_23
Build report Bioconductor build system, r-universe
biocViewsMetagenomics, Microbiome, MultipleComparison, Normalization, Software
Package Short Url https://bioconductor.org/packages/maaslin3/

Citation

From within R, enter citation("maaslin3"):

William Nickols, Jacob Nearing. maaslin3: "Refining and extending generalized multivariate linear models for meta-omic association discovery". doi:10.18129/B9.bioc.maaslin3, R package version 1.4.0, https://bioconductor.org/packages/maaslin3.

Generated from the package metadata; it may differ from the package's own citation.

Documentation

Download

Follow the installation instructions to use this package in your R session.

Source packagemaaslin3_1.4.0.tar.gz
Windows binary (x86_64)maaslin3_1.4.0.zip
macOS binary (arm64)maaslin3_1.4.0.tgz
macOS binary (x86_64)maaslin3_1.4.0.tgz
Dependencies

Depends: R (>= 4.4)

Imports: data.table, collapse, lmerTest, lme4, optparse, logging, mirai, multcomp, ggplot2, RColorBrewer, patchwork, scales, rlang, ggnewscale, survival, methods, BiocGenerics, reformulas

Suggests: knitr, testthat (>= 2.1.0), rmarkdown, markdown, kableExtra, dplyr, SummarizedExperiment, TreeSummarizedExperiment

Reverse dependencies

Imports Me (2): benchdamic, MMUPHin

Suggests Me (2): dar, miaViz