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immLynx

This is the released version of immLynx; for the devel version, see immLynx.

All versions 3.24 (devel), 3.23 (release)

Linking Advanced TCR Python Pipelines and Hugging Face Models in R


Bioconductor version: Release (3.23)

A comprehensive toolkit that bridges popular Python-based immune repertoire analysis tools and Hugging Face protein language models into the R environment. Provides unified interfaces for TCR distance calculations (tcrdist3), sequence generation probability (OLGA), selection inference (soNNia), clustering (clusTCR), protein embeddings (ESM-2), metaclone discovery (metaclonotypist). Fully compatible with the scRepertoire and immApex ecosystem for single-cell immune repertoire analysis.

Author: Nick Borcherding [aut, cre] ORCID iD ORCID: 0000-0003-1427-6342

Maintainer: Nick Borcherding <ncborch at gmail.com>

Citation (from within R, enter citation("immLynx")):

Nick Borcherding. immLynx: Linking Advanced TCR Python Pipelines and Hugging Face Models in R. doi:10.18129/B9.bioc.immLynx, R package version 1.0.0, https://bioconductor.org/packages/immLynx.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("immLynx")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("immLynx")
Advanced TCR Analysis with immLynx HTML R Script
Getting Started with immLynx HTML R Script
Reference ManualPDF
NEWSText
LICENSEText

Details

biocViews Annotation, Classification, Clustering, DimensionReduction, ImmunoOncology, MotifAnnotation, Sequencing, SingleCell, Software
Version1.0.0
In Bioconductor sinceBioC 3.23 (R-4.6) (< 6 months)
License MIT + file LICENSE
Depends R (>= 4.5.0)
Imports basilisk (>= 1.8.0), reticulate (>= 1.24), immApex, methods, S4Vectors, SingleCellExperiment, stats, SummarizedExperiment, utils
System Requirements
URLhttps://github.com/BorchLab/immLynx/
Bug Reportshttps://github.com/BorchLab/immLynx/issues
See More
Suggests BiocStyle, ggplot2, knitr, markdown, rmarkdown, scater, scran, scRepertoire, spelling, testthat (>= 3.0.0), withr
Linking To
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package immLynx_1.0.0.tar.gz
Windows Binary (x86_64) immLynx_1.0.0.zip
macOS Binary (big-sur-x86_64) immLynx_1.0.0.tgz
macOS Binary (sonoma-arm64) immLynx_1.0.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/immLynx
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/immLynx
Package Short Url https://bioconductor.org/packages/immLynx/
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