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TOP

This is the released version of TOP; for the devel version, see TOP.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17

TOP Constructs Transferable Model Across Gene Expression Platforms


Bioconductor version: Release (3.23)

TOP constructs a transferable model across gene expression platforms for prospective experiments. Such a transferable model can be trained to make predictions on independent validation data with an accuracy that is similar to a re-substituted model. The TOP procedure also has the flexibility to be adapted to suit the most common clinical response variables, including linear response, binomial and Cox PH models.

Author: Harry Robertson [aut, cre] ORCID iD ORCID: 0000-0001-9203-3894 , Nicholas Robertson [aut]

Maintainer: Harry Robertson <harry.robertson at sydney.edu.au>

Citation (from within R, enter citation("TOP")):

Harry Robertson, Nicholas Robertson. TOP: TOP Constructs Transferable Model Across Gene Expression Platforms. doi:10.18129/B9.bioc.TOP, R package version 1.12.0, https://bioconductor.org/packages/TOP.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("TOP")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("TOP")
"Introduction to TOP" HTML R Script
Reference ManualPDF

Details

biocViews GeneExpression, Software, Survival
Version1.12.0
In Bioconductor sinceBioC 3.17 (R-4.3) (3.5 years)
License GPL-3
Depends R (>= 4.1.0)
Imports assertthat, caret, ClassifyR, directPA, doParallel, dplyr, ggnewscale, ggplot2, ggraph, ggrepel, ggthemes, glmnet, Hmisc, igraph, latex2exp, limma, magrittr, methods, plotly, pROC, purrr, reshape2, stats, stringr, survival, tibble, tidygraph, tidyr, statmod
System Requirements
URLhttps://github.com/Harry25R/TOP
Bug Reportshttps://github.com/Harry25R/TOP/issues
See More
Suggests knitr, rmarkdown, BiocStyle, Biobase, curatedOvarianData, ggbeeswarm, ggsci, survminer, tidyverse
Linking To
Enhances
Depends On Me
Imports Me
Suggests Me ClassifyR
Links To Me
Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package TOP_1.12.0.tar.gz
Windows Binary (x86_64) TOP_1.12.0.zip
macOS Binary (big-sur-x86_64) TOP_1.12.0.tgz
macOS Binary (sonoma-arm64) TOP_1.12.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/TOP
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/TOP
Package Short Url https://bioconductor.org/packages/TOP/
Package Downloads ReportDownload Stats