SimFFPE
NGS Read Simulator for FFPE Tissue
Bioconductor version: Release (3.19)
The NGS (Next-Generation Sequencing) reads from FFPE (Formalin-Fixed Paraffin-Embedded) samples contain numerous artifact chimeric reads (ACRS), which can lead to false positive structural variant calls. These ACRs are derived from the combination of two single-stranded DNA (ss-DNA) fragments with short reverse complementary regions (SRCRs). This package simulates these artifact chimeric reads as well as normal reads for FFPE samples on the whole genome / several chromosomes / large regions.
Author: Lanying Wei [aut, cre]
Maintainer: Lanying Wei <lanying.wei at uni-muenster.de>
citation("SimFFPE")
):
Installation
To install this package, start R (version "4.4") and enter:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("SimFFPE")
For older versions of R, please refer to the appropriate Bioconductor release.
Documentation
To view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("SimFFPE")
An introduction to SimFFPE | R Script | |
Reference Manual | ||
NEWS | Text |
Details
biocViews | Alignment, DataImport, MultipleComparison, SequenceMatching, Sequencing, Software |
Version | 1.16.0 |
In Bioconductor since | BioC 3.11 (R-4.0) (4.5 years) |
License | LGPL-3 |
Depends | Biostrings |
Imports | dplyr, foreach, doParallel, truncnorm, GenomicRanges, IRanges, Rsamtools, parallel, graphics, stats, utils, methods |
System Requirements | |
URL |
See More
Suggests | BiocStyle |
Linking To | |
Enhances | |
Depends On Me | |
Imports Me | |
Suggests Me | |
Links To Me | |
Build Report | Build Report |
Package Archives
Follow Installation instructions to use this package in your R session.
Source Package | SimFFPE_1.16.0.tar.gz |
Windows Binary | SimFFPE_1.16.0.zip |
macOS Binary (x86_64) | SimFFPE_1.16.0.tgz |
macOS Binary (arm64) | SimFFPE_1.16.0.tgz |
Source Repository | git clone https://git.bioconductor.org/packages/SimFFPE |
Source Repository (Developer Access) | git clone git@git.bioconductor.org:packages/SimFFPE |
Bioc Package Browser | https://code.bioconductor.org/browse/SimFFPE/ |
Package Short Url | https://bioconductor.org/packages/SimFFPE/ |
Package Downloads Report | Download Stats |