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SPIAT

This is the released version of SPIAT; for the devel version, see SPIAT.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16

Spatial Image Analysis of Tissues


Bioconductor version: Release (3.23)

SPIAT (**Sp**atial **I**mage **A**nalysis of **T**issues) is an R package with a suite of data processing, quality control, visualization and data analysis tools. SPIAT is compatible with data generated from single-cell spatial proteomics platforms (e.g. OPAL, CODEX, MIBI, cellprofiler). SPIAT reads spatial data in the form of X and Y coordinates of cells, marker intensities and cell phenotypes. SPIAT includes six analysis modules that allow visualization, calculation of cell colocalization, categorization of the immune microenvironment relative to tumor areas, analysis of cellular neighborhoods, and the quantification of spatial heterogeneity, providing a comprehensive toolkit for spatial data analysis.

Author: Anna Trigos [aut] ORCID iD ORCID: 0000-0002-5915-2952 , Yuzhou Feng [aut, cre] ORCID iD ORCID: 0000-0002-2955-4053 , Tianpei Yang [aut], Mabel Li [aut], John Zhu [aut], Volkan Ozcoban [aut], Maria Doyle [aut]

Maintainer: Yuzhou Feng <yuzhou0610 at gmail.com>

Citation (from within R, enter citation("SPIAT")):

Anna Trigos, Yuzhou Feng, Tianpei Yang, Mabel Li, John Zhu, Volkan Ozcoban, Maria Doyle. SPIAT: Spatial Image Analysis of Tissues. doi:10.18129/B9.bioc.SPIAT, R package version 1.14.0, https://bioconductor.org/packages/SPIAT.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("SPIAT")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("SPIAT")
Basic analyses with SPIAT HTML R Script
Quantifying cell colocalisation with SPIAT HTML R Script
Reading in data and data formatting in SPIAT HTML R Script
Identifying cellular neighborhood with SPIAT HTML R Script
Quality control and visualisation with SPIAT HTML R Script
Spatial heterogeneity with SPIAT HTML R Script
Overview of the SPIAT package HTML R Script
Characterising tissue structure with SPIAT HTML R Script
Reference ManualPDF
NEWSText
LICENSEText

Details

biocViews BiomedicalInformatics, CellBiology, Clustering, DataImport, ImmunoOncology, QualityControl, SingleCell, Software, Spatial, Visualization
Version1.14.0
In Bioconductor sinceBioC 3.16 (R-4.2) (4 years)
License Artistic-2.0 + file LICENSE
Depends R (>= 4.2.0), SpatialExperiment (>= 1.8.0)
Imports apcluster (>= 1.4.7), ggplot2 (>= 3.2.1), gridExtra (>= 2.3), gtools (>= 3.8.1), reshape2 (>= 1.4.3), dplyr (>= 0.8.3), RANN (>= 2.6.1), pracma (>= 2.2.5), dbscan (>= 1.1-5), mmand (>= 1.5.4), tibble (>= 2.1.3), grDevices, stats, utils, vroom, dittoSeq, spatstat.geom, methods, spatstat.explore, raster, sp, SummarizedExperiment, rlang
System Requirements
URLhttps://trigosteam.github.io/SPIAT/
Bug Reportshttps://github.com/trigosteam/SPIAT/issues
See More
Suggests BiocStyle, plotly (>= 4.9.0), knitr, rmarkdown, pkgdown, testthat, graphics, alphahull, Rtsne, umap, ComplexHeatmap, elsa
Linking To
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Depends On Me
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Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package SPIAT_1.14.0.tar.gz
Windows Binary (x86_64) SPIAT_1.14.0.zip
macOS Binary (big-sur-x86_64) SPIAT_1.14.0.tgz
macOS Binary (sonoma-arm64) SPIAT_1.14.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/SPIAT
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/SPIAT
Package Short Url https://bioconductor.org/packages/SPIAT/
Package Downloads ReportDownload Stats