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Pirat

This is the released version of Pirat; for the devel version, see Pirat.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20

Precursor or Peptide Imputation under Random Truncation


Bioconductor version: Release (3.23)

Pirat enables the imputation of missing values (either MNARs or MCARs) in bottom-up LC-MS/MS proteomics data using a penalized maximum likelihood strategy. It does not require any parameter tuning, it models the instrument censorship from the data available. It accounts for sibling peptides correlations and it can leverage complementary transcriptomics measurements.

Author: Lucas Etourneau [cre, aut] ORCID iD ORCID: 0000-0002-8670-808X , Laura Fancello [aut], Manon Gaudin [aut], Samuel Wieczorek [aut] ORCID iD ORCID: 0000-0002-5016-1203 , Nelle Varoquaux [aut], Thomas Burger [aut]

Maintainer: Lucas Etourneau <lucas.etourneau at gmail.com>

Citation (from within R, enter citation("Pirat")):

Lucas Etourneau, Laura Fancello, Manon Gaudin, Samuel Wieczorek, Nelle Varoquaux, Thomas Burger. Pirat: Precursor or Peptide Imputation under Random Truncation. doi:10.18129/B9.bioc.Pirat, R package version 1.6.1, https://bioconductor.org/packages/Pirat.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("Pirat")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("Pirat")
Pirat-vignette HTML R Script
Reference ManualPDF
NEWSText

Details

biocViews MassSpectrometry, Preprocessing, Proteomics, Software
Version1.6.1
In Bioconductor sinceBioC 3.20 (R-4.4) (2 years)
License GPL-2
Depends R (>= 4.5.0)
Imports basilisk, reticulate, progress, ggplot2, MASS, invgamma, grDevices, stats, graphics, SummarizedExperiment, S4Vectors
System Requirements
URLhttps://github.com/edyp-lab/Pirat
Bug Reportshttps://github.com/edyp-lab/Pirat/issues
See More
Suggests knitr, BiocStyle
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Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package Pirat_1.6.1.tar.gz
Windows Binary (x86_64) Pirat_1.6.1.zip
macOS Binary (big-sur-x86_64) Pirat_1.6.1.tgz
macOS Binary (sonoma-arm64) Pirat_1.6.1.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/Pirat
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/Pirat
Package Short Url https://bioconductor.org/packages/Pirat/
Package Downloads ReportDownload Stats
Old Source Packages for BioC 3.23Source Archive