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MSstatsPTM

This is the released version of MSstatsPTM; for the devel version, see MSstatsPTM.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14, 3.13, 3.12

Statistical Characterization of Post-translational Modifications


Bioconductor version: Release (3.23)

MSstatsPTM provides general statistical methods for quantitative characterization of post-translational modifications (PTMs). Supports DDA, DIA, SRM, and tandem mass tag (TMT) labeling. Typically, the analysis involves the quantification of PTM sites (i.e., modified residues) and their corresponding proteins, as well as the integration of the quantification results. MSstatsPTM provides functions for summarization, estimation of PTM site abundance, and detection of changes in PTMs across experimental conditions.

Author: Devon Kohler [aut], Tsung-Heng Tsai [aut], Anthony Wu [aut, cre], Deril Raju [aut], Ting Huang [aut], Mateusz Staniak [aut], Meena Choi [aut], Olga Vitek [aut]

Maintainer: Anthony Wu <wu.anthon at northeastern.edu>

Citation (from within R, enter citation("MSstatsPTM")):

Devon Kohler, Tsung-Heng Tsai, Anthony Wu, Deril Raju, Ting Huang, Mateusz Staniak, Meena Choi, Olga Vitek. MSstatsPTM: Statistical Characterization of Post-translational Modifications. doi:10.18129/B9.bioc.MSstatsPTM, R package version 2.14.0, https://bioconductor.org/packages/MSstatsPTM.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("MSstatsPTM")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("MSstatsPTM")
MSstatsPTM LabelFree Workflow HTML R Script
MSstatsPTM TMT Workflow HTML R Script
Reference ManualPDF

Details

biocViews DifferentialExpression, ImmunoOncology, MassSpectrometry, Normalization, OneChannel, Proteomics, QualityControl, Software, TwoChannel
Version2.14.0
In Bioconductor sinceBioC 3.12 (R-4.0) (6 years)
License Artistic-2.0
Depends R (>= 4.3)
Imports dplyr, gridExtra, stringr, stats, ggplot2, stringi, grDevices, MSstatsTMT, MSstatsConvert (>= 1.19.1), MSstats, data.table, Rcpp, Biostrings, checkmate, ggrepel, plotly, htmltools, rlang
System Requirements
URLhttps://vitek-lab.github.io/MSstatsPTM/
Bug Reportshttps://github.com/Vitek-Lab/MSstatsPTM/issues
See More
Suggests knitr, rmarkdown, tinytest, covr, mockery, arrow, testthat (>= 3.0.0)
Linking To Rcpp
Enhances
Depends On Me
Imports Me MSstatsLiP, MSstatsShiny
Suggests Me
Links To Me
Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package MSstatsPTM_2.14.0.tar.gz
Windows Binary (x86_64) MSstatsPTM_2.14.0.zip
macOS Binary (big-sur-x86_64) MSstatsPTM_2.14.0.tgz
macOS Binary (sonoma-arm64) MSstatsPTM_2.14.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/MSstatsPTM
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/MSstatsPTM
Package Short Url https://bioconductor.org/packages/MSstatsPTM/
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