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LinkHD: a versatile framework to explore and integrate heterogeneous data

Bioconductor version: Release (3.19)

Here we present Link-HD, an approach to integrate heterogeneous datasets, as a generalization of STATIS-ACT (“Structuration des Tableaux A Trois Indices de la Statistique–Analyse Conjointe de Tableaux”), a family of methods to join and compare information from multiple subspaces. However, STATIS-ACT has some drawbacks since it only allows continuous data and it is unable to establish relationships between samples and features. In order to tackle these constraints, we incorporate multiple distance options and a linear regression based Biplot model in order to stablish relationships between observations and variable and perform variable selection.

Author: Laura M. Zingaretti [aut, cre]

Maintainer: "Laura M Zingaretti" <m.lau.zingaretti at>

Citation (from within R, enter citation("LinkHD")):


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Annotating Genomic Variants HTML R Script
Reference Manual PDF


biocViews Classification, MultipleComparison, Regression, Software
Version 1.18.0
In Bioconductor since BioC 3.10 (R-3.6) (4.5 years)
License GPL-3
Depends R (>= 3.6.0), methods, ggplot2, stats
Imports scales, cluster, graphics, ggpubr, gridExtra, vegan, rio, MultiAssayExperiment, emmeans, reshape2, data.table
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Suggests MASS (>= 7.3.0), knitr, rmarkdown, BiocStyle
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Source Package LinkHD_1.18.0.tar.gz
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