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DEqMS

This is the released version of DEqMS; for the devel version, see DEqMS.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14, 3.13, 3.12, 3.11, 3.10, 3.9, 3.8

a tool to perform statistical analysis of differential protein expression for quantitative proteomics data.


Bioconductor version: Release (3.23)

DEqMS is developped on top of Limma. However, Limma assumes same prior variance for all genes. In proteomics, the accuracy of protein abundance estimates varies by the number of peptides/PSMs quantified in both label-free and labelled data. Proteins quantification by multiple peptides or PSMs are more accurate. DEqMS package is able to estimate different prior variances for proteins quantified by different number of PSMs/peptides, therefore acchieving better accuracy. The package can be applied to analyze both label-free and labelled proteomics data.

Author: Yafeng Zhu

Maintainer: Yafeng Zhu <yafeng.zhu at outlook.com>

Citation (from within R, enter citation("DEqMS")):

Yafeng Zhu. DEqMS: a tool to perform statistical analysis of differential protein expression for quantitative proteomics data. doi:10.18129/B9.bioc.DEqMS, R package version 1.30.0, https://bioconductor.org/packages/DEqMS.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("DEqMS")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("DEqMS")
DEqMS R Markdown vignettes HTML R Script
Reference ManualPDF
NEWSText

Details

biocViews Bayesian, DifferentialExpression, ExperimentHubSoftware, ImmunoOncology, MassSpectrometry, MultipleComparison, Normalization, Preprocessing, Proteomics, Software
Version1.30.0
In Bioconductor sinceBioC 3.8 (R-3.5) (8 years)
License LGPL
Depends R (>= 3.5), graphics, stats, ggplot2, matrixStats, dplyr, limma (>= 3.34)
Imports
System Requirements
URL
Bug Reportshttps://github.com/yafeng/DEqMS/issues
See More
Suggests BiocStyle, knitr, rmarkdown, markdown, plyr, reshape2, utils, ggrepel, ExperimentHub, LSD
Linking To
Enhances
Depends On Me
Imports Me PRONE
Suggests Me
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Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package DEqMS_1.30.0.tar.gz
Windows Binary (x86_64)
macOS Binary (big-sur-x86_64) DEqMS_1.30.0.tgz
macOS Binary (sonoma-arm64) DEqMS_1.30.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/DEqMS
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/DEqMS
Package Short Url https://bioconductor.org/packages/DEqMS/
Package Downloads ReportDownload Stats