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Add-on to CellNOptR: Discretized time treatments

Bioconductor version: Release (3.18)

This add-on to the package CellNOptR handles time-course data, as opposed to steady state data in CellNOptR. It scales the simulation step to allow comparison and model fitting for time-course data. Future versions will optimize delays and strengths for each edge.

Author: A. MacNamara

Maintainer: A. MacNamara <aidan.macnamara at ebi.ac.uk>

Citation (from within R, enter citation("CNORdt")):


To install this package, start R (version "4.3") and enter:

if (!require("BiocManager", quietly = TRUE))


For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:

Using multiple time points to train logic models to data PDF R Script
Reference Manual PDF


biocViews CellBasedAssays, CellBiology, ImmunoOncology, Proteomics, Software, TimeCourse
Version 1.44.0
In Bioconductor since BioC 2.11 (R-2.15) (11.5 years)
License GPL-2
Depends R (>= 1.8.0), CellNOptR(>= 0.99), abind
System Requirements
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package CNORdt_1.44.0.tar.gz
Windows Binary CNORdt_1.44.0.zip (64-bit only)
macOS Binary (x86_64) CNORdt_1.44.0.tgz
macOS Binary (arm64) CNORdt_1.44.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/CNORdt
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/CNORdt
Bioc Package Browser https://code.bioconductor.org/browse/CNORdt/
Package Short Url https://bioconductor.org/packages/CNORdt/
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