Bioconductor Developer Survey 2026 Now Open!

methylclock

This is the released version of methylclock; for the devel version, see methylclock.

All Bioconductor versions of methylclock

3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14

Methylclock - DNA methylation-based clocks

Bioconductor version: 3.23 · Package version: 1.18.0

This package allows to estimate chronological and gestational DNA methylation (DNAm) age as well as biological age using different methylation clocks. Chronological DNAm age (in years) : Horvath's clock, Hannum's clock, BNN, Horvath's skin+blood clock, PedBE clock and Wu's clock. Gestational DNAm age : Knight's clock, Bohlin's clock, Mayne's clock and Lee's clocks. Biological DNAm clocks : Levine's clock and Telomere Length's clock.

Author: Dolors Pelegri-Siso [aut, cre] ORCID iD ORCID: 0000-0002-5993-3003 , Juan R. Gonzalez [aut] ORCID iD ORCID: 0000-0003-3267-2146

Maintainer: Dolors Pelegri-Siso <dolors.pelegri at isglobal.org>

DOI: 10.18129/B9.bioc.methylclock

Citation

From within R, enter citation("methylclock"):

Dolors Pelegri-Siso, Juan R. Gonzalez. methylclock: Methylclock - DNA methylation-based clocks. doi:10.18129/B9.bioc.methylclock, R package version 1.18.0, https://bioconductor.org/packages/methylclock.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("methylclock")

For older versions of R, please refer to the appropriate Bioconductor release.

Details

Version1.18.0
LicenseMIT + file LICENSE
URLhttps://github.com/isglobal-brge/methylclock
Bug Reportshttps://github.com/isglobal-brge/methylclock/issues
Last updated2026-04-28
In Bioconductor sinceBioC 3.14 (R-4.1) (4 years)
Downloads rank830 of 2,418
Source branchRELEASE_3_23
Build report Bioconductor build system, r-universe
biocViewsBiologicalQuestion, DNAMethylation, Normalization, Preprocessing, Software, StatisticalMethod
Package Short Url https://bioconductor.org/packages/methylclock/

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("methylclock")
Chronological and gestational DNAm age estimation using different methylation-based clocks HTML R Script
Reference ManualPDF
NEWSText

Download

Follow the installation instructions to use this package in your R session.

Source packagemethylclock_1.18.0.tar.gz
Windows binary (x86_64)methylclock_1.18.0.zip
macOS binary (arm64)methylclock_1.18.0.tgz
macOS binary (x86_64)methylclock_1.18.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/methylclock
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/methylclock
Package Downloads ReportDownload Stats
Dependencies

Depends: R (>= 4.1.0), methylclockData, devtools, quadprog

Imports: Rcpp (>= 1.0.6), ExperimentHub, dplyr, impute, PerformanceAnalytics, Biobase, ggpmisc, tidyverse, ggplot2, ggpubr, minfi, tibble, RPMM, stats, graphics, tidyr, gridExtra, preprocessCore, dynamicTreeCut, planet

LinkingTo: Rcpp

Suggests: BiocStyle, knitr, GEOquery, rmarkdown