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HiBED

This is the development version of HiBED; for the stable release version, see HiBED.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18

HiBED


Bioconductor version: Development (3.24)

Hierarchical deconvolution for extensive cell type resolution in the human brain using DNA methylation. The HiBED deconvolution estimates proportions up to 7 cell types (GABAergic neurons, glutamatergic neurons, astrocytes, microglial cells, oligodendrocytes, endothelial cells, and stromal cells) in bulk brain tissues.

Author: Ze Zhang [cre, aut] ORCID iD ORCID: 0000-0001-9854-5823 , Lucas A. Salas [aut]

Maintainer: Ze Zhang <ze.zhang.gr at dartmouth.edu>

Citation (from within R, enter citation("HiBED")):

Ze Zhang, Lucas A. Salas. HiBED: HiBED. doi:10.18129/B9.bioc.HiBED, R package version 1.11.0, https://bioconductor.org/packages/HiBED.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("HiBED")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("HiBED")
HiBED HTML R Script
Reference ManualPDF
NEWSText

Details

biocViews ExperimentData, Genome, Homo_sapiens_Data, MethylationArrayData, MicroarrayData, PackageTypeData, Tissue
Version1.11.0
In Bioconductor sinceBioC 3.18 (R-4.3) (3 years)
License GPL-3
Depends R (>= 3.5.0)
Imports dplyr, FlowSorted.Blood.EPIC, tibble, FlowSorted.DLPFC.450k, minfi, utils, AnnotationHub, SummarizedExperiment
System Requirements
URLhttps://github.com/SalasLab/HiBED
Bug Reportshttps://github.com/SalasLab/HiBED/issues.
See More
Suggests knitr, rmarkdown, testthat, IlluminaHumanMethylation450kmanifest
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Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package HiBED_1.11.0.tar.gz
Windows Binary (x86_64)
macOS Binary (big-sur-x86_64)
macOS Binary (sonoma-arm64)
Source Repositorygit clone https://git.bioconductor.org/packages/HiBED
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/HiBED
Package Short Url https://bioconductor.org/packages/HiBED/
Package Downloads ReportDownload Stats