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xCell2

This is the development version of xCell2; for the stable release version, see xCell2.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21

A Tool for Generic Cell Type Enrichment Analysis


Bioconductor version: Development (3.24)

xCell2 provides methods for cell type enrichment analysis using cell type signatures. It includes three main functions - 1. xCell2Train for training custom references objects from bulk or single-cell RNA-seq datasets. 2. xCell2Analysis for conducting the cell type enrichment analysis using the custom reference. 3. xCell2GetLineage for identifying dependencies between different cell types using ontology.

Author: Almog Angel [aut, cre] ORCID iD ORCID: 0009-0001-3297-6935 , Dvir Aran [aut] ORCID iD ORCID: 0000-0001-6334-5039

Maintainer: Almog Angel <almog.angel at campus.technion.ac.il>

Citation (from within R, enter citation("xCell2")):

Almog Angel, Dvir Aran. xCell2: A Tool for Generic Cell Type Enrichment Analysis. doi:10.18129/B9.bioc.xCell2, R package version 1.5.0, https://bioconductor.org/packages/xCell2.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("xCell2")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("xCell2")
Introduction to xCell2 HTML R Script
Reference ManualPDF
NEWSText

Details

biocViews DifferentialExpression, GeneExpression, GeneSetEnrichment, ImmunoOncology, Microarray, RNASeq, SingleCell, Software, Transcriptomics
Version1.5.0
In Bioconductor sinceBioC 3.21 (R-4.5) (1.5 years)
License GPL (>= 3)
Depends R (>= 4.0.0)
Imports SummarizedExperiment, SingleCellExperiment, Rfast, singscore, AnnotationHub, ontologyIndex, tibble, dplyr, BiocParallel, Matrix, minpack.lm, pracma, methods, readr, magrittr, progress, quadprog
System Requirements
URLhttps://github.com/AlmogAngel/xCell2
Bug Reportshttps://github.com/AlmogAngel/xCell2/issues
See More
Suggests testthat, knitr, rmarkdown, ggplot2, randomForest, tidyr, EnhancedVolcano, BiocStyle
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Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package xCell2_1.5.0.tar.gz
Windows Binary (x86_64) xCell2_1.5.0.zip (64-bit only)
macOS Binary (big-sur-x86_64) xCell2_1.5.0.tgz
macOS Binary (sonoma-arm64) xCell2_1.5.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/xCell2
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/xCell2
Package Short Url https://bioconductor.org/packages/xCell2/
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