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strainspy

This is the development version of strainspy; to use it, please install the devel version of Bioconductor.

Strain Level Microbiome Wide Association Studies


Bioconductor version: Development (3.24)

Fits statistical models to detect microbial strains associated with a phenotype. For small sample sizes, models can be fitted using empirical Bayes maximum a posteriori (MAP) priors to improve detection power. Supports various experimental design scenarios, including repeated measures.

Author: Gerry Tonkin-Hill [aut], Sudaraka Mallawaarachchi [aut, cre] ORCID iD ORCID: 0000-0001-8899-3323

Maintainer: Sudaraka Mallawaarachchi <smallawaarachchi at gmail.com>

Citation (from within R, enter citation("strainspy")):

Gerry Tonkin-Hill, Sudaraka Mallawaarachchi. strainspy: Strain Level Microbiome Wide Association Studies. doi:10.18129/B9.bioc.strainspy, R package version 0.99.3, https://bioconductor.org/packages/strainspy.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("strainspy")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("strainspy")
strainspy Workflow HTML R Script
Reference ManualPDF
NEWSText
LICENSEText

Details

biocViews DifferentialExpression, ExperimentalDesign, Metagenomics, MicrobialStrain, Microbiome, Regression, Sequencing, Software
Version0.99.3
In Bioconductor sinceBioC 3.24 (R-4.6)
License MIT + file LICENSE
Depends R (>= 4.1.0)
Imports ape, BiocParallel, data.table, dplyr, ggforce, ggplot2, ggrepel, ggthemes, ggtree, glmmTMB, graphics, grDevices, harmonicmeanp, lmerTest, magrittr, Matrix, methods, patchwork, purrr, R.utils (>= 2.13.0), S4Vectors, stats, stringr, SummarizedExperiment, rlang, tibble, tidyr, tools, utils, viridis
System Requirements
URLhttps://github.com/gtonkinhill/strainspy https://sudaraka88.r-universe.dev/strainspy
Bug Reportshttps://github.com/gtonkinhill/strainspy/issues
See More
Suggests betareg, BiocStyle, compositions, fastglm, future, gamlss, gamlss.dist, knitr, mgcv, rmarkdown, testthat (>= 3.0.0), vegan, emmeans
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Depends On Me
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Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package strainspy_0.99.3.tar.gz
Windows Binary (x86_64) strainspy_0.99.3.zip
macOS Binary (big-sur-x86_64) strainspy_0.99.3.tgz
macOS Binary (sonoma-arm64) strainspy_0.99.3.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/strainspy
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/strainspy
Package Short Url https://bioconductor.org/packages/strainspy/
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