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speckle

This is the development version of speckle; for the stable release version, see speckle.

All Bioconductor versions of speckle

3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17

Statistical methods for analysing single cell RNA-seq data

Bioconductor version: 3.24 · Package version: 1.13.0

The speckle package contains functions for the analysis of single cell RNA-seq data. The speckle package currently contains functions to analyse differences in cell type proportions. There are also functions to estimate the parameters of the Beta distribution based on a given counts matrix, and a function to normalise a counts matrix to the median library size. There are plotting functions to visualise cell type proportions and the mean-variance relationship in cell type proportions and counts. As our research into specialised analyses of single cell data continues we anticipate that the package will be updated with new functions.

Author: Belinda Phipson [aut, cre]

Maintainer: Belinda Phipson <phipson.b at wehi.edu.au>

DOI: 10.18129/B9.bioc.speckle

Citation

From within R, enter citation("speckle"):

Belinda Phipson. speckle: Statistical methods for analysing single cell RNA-seq data. doi:10.18129/B9.bioc.speckle, R package version 1.13.0, https://bioconductor.org/packages/speckle.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("speckle")

For older versions of R, please refer to the appropriate Bioconductor release.

Details

Version1.13.0
LicenseGPL-3
Last updated2026-04-28
In Bioconductor sinceBioC 3.17 (R-4.3) (3 years)
Downloads rank350 of 2,456
Source branchdevel
Build report Bioconductor build system, r-universe
biocViewsGeneExpression, RNASeq, Regression, SingleCell, Software
Package Short Url https://bioconductor.org/packages/speckle/

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("speckle")
speckle: statistical methods for analysing single cell RNA-seq data HTML R Script
Reference ManualPDF
NEWSText

Download

Follow the installation instructions to use this package in your R session.

Source packagespeckle_1.13.0.tar.gz
Windows binary (x86_64)speckle_1.13.0.zip
macOS binary (arm64)speckle_1.13.0.tgz
macOS binary (x86_64)speckle_1.13.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/speckle
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/speckle
Package Downloads ReportDownload Stats
Dependencies

Depends: R (>= 4.2.0)

Imports: limma, edgeR, SingleCellExperiment, Seurat, ggplot2, methods, stats, grDevices, graphics

Suggests: BiocStyle, knitr, rmarkdown, statmod, CellBench, scater, patchwork, jsonlite, vdiffr, testthat (>= 3.0.0)