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qsvaR

This is the development version of qsvaR; for the stable release version, see qsvaR.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15

Generate Quality Surrogate Variable Analysis for Degradation Correction


Bioconductor version: Development (3.24)

The qsvaR package contains functions for removing the effect of degration in rna-seq data from postmortem brain tissue. The package is equipped to help users generate principal components associated with degradation. The components can be used in differential expression analysis to remove the effects of degradation.

Author: Joshua Stolz [aut] ORCID iD ORCID: 0000-0001-5694-5247 , Hedia Tnani [ctb] ORCID iD ORCID: 0000-0002-0380-9740 , Leonardo Collado-Torres [ctb] ORCID iD ORCID: 0000-0003-2140-308X , Nicholas J. Eagles [aut, cre] ORCID iD ORCID: 0000-0002-9808-5254

Maintainer: Nicholas J. Eagles <nickeagles77 at gmail.com>

Citation (from within R, enter citation("qsvaR")):

Joshua Stolz, Nicholas J. Eagles. qsvaR: Generate Quality Surrogate Variable Analysis for Degradation Correction. doi:10.18129/B9.bioc.qsvaR, R package version 1.17.0, https://bioconductor.org/packages/qsvaR.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("qsvaR")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("qsvaR")
Introduction to qsvaR HTML R Script
Reference ManualPDF
NEWSText

Details

biocViews BiologicalQuestion, Coverage, DifferentialExpression, Normalization, Sequencing, Software, WorkflowStep
Version1.17.0
In Bioconductor sinceBioC 3.15 (R-4.2) (4.5 years)
License Artistic-2.0
Depends R (>= 4.2), SummarizedExperiment
Imports dplyr, sva, stats, ggplot2, rlang, methods
System Requirements
URLhttps://github.com/LieberInstitute/qsvaR
Bug Reportshttps://support.bioconductor.org/t/qsvaR
See More
Suggests BiocFileCache, BiocStyle, covr, knitr, limma, RefManageR, rmarkdown, sessioninfo, testthat (>= 3.0.0)
Linking To
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Depends On Me
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Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package qsvaR_1.17.0.tar.gz
Windows Binary (x86_64) qsvaR_1.17.0.zip
macOS Binary (big-sur-x86_64) qsvaR_1.17.0.tgz
macOS Binary (sonoma-arm64) qsvaR_1.17.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/qsvaR
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/qsvaR
Package Short Url https://bioconductor.org/packages/qsvaR/
Package Downloads ReportDownload Stats