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pepVet

This is the development version of pepVet; to use it, please install the devel version of Bioconductor.

Evaluate Proteolytic Digests for Proteomics Workflows


Bioconductor version: Development (3.24)

Simulates proteolytic digestion, scores the resulting peptides for LC-MS/MS suitability, compares candidate enzymes, and reports digest quality at the protein level. Supports 40 cleaver-compatible enzyme rules, workflow presets, peptide mass and pI calculations, sequence-local cleavage-efficiency annotations, and proteome-aware uniqueness scoring. Evaluates multi-FASTA files in batches with per-protein triage and proteome-level summaries. Exports peptide lists for Skyline and generic downstream tools and prints styled console reports.

Author: Enes K. Ergin [aut, cre] ORCID iD ORCID: 0000-0001-9810-7399

Maintainer: Enes K. Ergin <eneskemalergin at gmail.com>

Citation (from within R, enter citation("pepVet")):

Enes K. Ergin. pepVet: Evaluate Proteolytic Digests for Proteomics Workflows. doi:10.18129/B9.bioc.pepVet, R package version 0.99.1, https://bioconductor.org/packages/pepVet.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("pepVet")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("pepVet")
Getting Started with pepVet HTML R Script
pepVet Compared to Other Tools HTML R Script
Reference ManualPDF
NEWSText
LICENSEText

Details

biocViews MassSpectrometry, Proteomics, QualityControl, Software
Version0.99.1
In Bioconductor sinceBioC 3.24 (R-4.6)
License MIT + file LICENSE
Depends R (>= 4.5.0)
Imports Biostrings, cleaver, cli, IRanges, rlang, tibble
System Requirements
URLhttps://github.com/LangeLab/pepVet https://langelab.github.io/pepVet/
Bug Reportshttps://github.com/LangeLab/pepVet/issues
See More
Suggests BiocStyle, ggplot2, patchwork, ragg, testthat (>= 3.0.0), withr, knitr, rmarkdown
Linking To
Enhances
Depends On Me
Imports Me
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Links To Me
Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package pepVet_0.99.1.tar.gz
Windows Binary (x86_64) pepVet_0.99.1.zip
macOS Binary (big-sur-x86_64) pepVet_0.99.1.tgz
macOS Binary (sonoma-arm64) pepVet_0.99.1.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/pepVet
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/pepVet
Package Short Url https://bioconductor.org/packages/pepVet/
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