Bioconductor Developer Survey 2026 Now Open!

karioCaS

This is the development version of karioCaS; to use it, please install the devel version of Bioconductor.

Kraken Confidence Scores for Reliable Domain-Specific Microbiota Inference and Discovery


Bioconductor version: Development (3.24)

Provides a comprehensive framework for analyzing Kraken2 metagenomic classification using multiple confidence scores. karioCaS implements a robust comparative approach to evaluate taxonomic stability across different stringency levels, facilitating the identification of reliable microbiota components and the discovery of potentially novel or unrepresented species. A key innovation is its domain-specific analysis, separately processing Bacteria, Archaea, Eukaryota, and Viruses to ensure balanced visibility of all biological domains. Includes high-quality visualization tools for retention rates, shared taxa (Upset plots), and stability heatmaps.

Author: Thiago Parente [aut, cre] ORCID iD ORCID: 0000-0001-7501-726X , Fiocruz [fnd], IOC-Fiocruz [fnd], CAPES [fnd]

Maintainer: Thiago Parente <thiago.parente at fiocruz.br>

Citation (from within R, enter citation("karioCaS")):

Thiago Parente. karioCaS: Kraken Confidence Scores for Reliable Domain-Specific Microbiota Inference and Discovery. doi:10.18129/B9.bioc.karioCaS, R package version 0.99.16, https://bioconductor.org/packages/karioCaS.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("karioCaS")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("karioCaS")
karioCaS: Kraken Confidence Scores Exploration HTML
Reference ManualPDF
NEWSText

Details

biocViews DataImport, Metagenomics, Microbiome, Software
Version0.99.16
In Bioconductor sinceBioC 3.24 (R-4.6)
License GPL (>= 3)
Depends R (>= 4.5.0)
Imports ggplot2, patchwork, UpSetR, dplyr, readr, stringr, tidyr, scales, ggtext, SummarizedExperiment, TreeSummarizedExperiment, S4Vectors, forcats, tibble, methods, rlang, grid, grDevices, stats, utils
System Requirements
URLhttps://github.com/thiagoparentefiocruz/karioCaS
Bug Reportshttps://github.com/thiagoparentefiocruz/karioCaS/issues
See More
Suggests BiocStyle, knitr, rmarkdown, testthat (>= 3.0.0)
Linking To
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package
Windows Binary (x86_64)
macOS Binary (big-sur-x86_64)
macOS Binary (sonoma-arm64)
Source Repositorygit clone https://git.bioconductor.org/packages/karioCaS
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/karioCaS
Package Short Url https://bioconductor.org/packages/karioCaS/
Package Downloads ReportDownload Stats