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gage

This is the development version of gage; for the stable release version, see gage.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14, 3.13, 3.12, 3.11, 3.10, 3.9, 3.8, 3.7, 3.6, 3.5, 3.4, 3.3, 3.2, 3.1, 3.0, 2.14, 2.13, 2.12, 2.11, 2.10, 2.9, 2.8, 2.7

Generally Applicable Gene-set Enrichment for Pathway Analysis


Bioconductor version: Development (3.24)

GAGE is a published method for gene set (enrichment or GSEA) or pathway analysis. GAGE is generally applicable independent of microarray or RNA-Seq data attributes including sample sizes, experimental designs, assay platforms, and other types of heterogeneity, and consistently achieves superior performance over other frequently used methods. In gage package, we provide functions for basic GAGE analysis, result processing and presentation. We have also built pipeline routines for of multiple GAGE analyses in a batch, comparison between parallel analyses, and combined analysis of heterogeneous data from different sources/studies. In addition, we provide demo microarray data and commonly used gene set data based on KEGG pathways and GO terms. These funtions and data are also useful for gene set analysis using other methods.

Author: Weijun Luo

Maintainer: Weijun Luo <luo_weijun at yahoo.com>

Citation (from within R, enter citation("gage")):

Weijun Luo. gage: Generally Applicable Gene-set Enrichment for Pathway Analysis. doi:10.18129/B9.bioc.gage, R package version 2.63.0, https://bioconductor.org/packages/gage.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("gage")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("gage")
Gene set and data preparation PDF R Script
Generally Applicable Gene-set/Pathway Analysis PDF R Script
RNA-Seq Data Pathway and Gene-set Analysis Workflows PDF R Script
Reference ManualPDF
NEWSText

Details

biocViews DifferentialExpression, GO, GeneExpression, GeneSetEnrichment, Genetics, Microarray, MultipleComparison, OneChannel, Pathways, RNASeq, Sequencing, Software, SystemsBiology, TwoChannel
Version2.63.0
In Bioconductor sinceBioC 2.7 (R-2.12) (16 years)
License GPL (>=2.0)
Depends R (>= 3.5.0)
Imports graph, KEGGREST, AnnotationDbi, GO.db
System Requirements
URLhttps://github.com/datapplab/gage http://www.biomedcentral.com/1471-2105/10/161
See More
Suggests pathview, gageData, org.Hs.eg.db, hgu133a.db, GSEABase, Rsamtools, GenomicAlignments, TxDb.Hsapiens.UCSC.hg19.knownGene, DESeq2, edgeR, limma
Linking To
Enhances
Depends On Me EGSEA
Imports Me postNet
Suggests Me FGNet, gageData, pathview, SBGNview
Links To Me
Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package gage_2.63.0.tar.gz
Windows Binary (x86_64) gage_2.63.0.zip
macOS Binary (big-sur-x86_64) gage_2.63.0.tgz
macOS Binary (sonoma-arm64) gage_2.63.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/gage
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/gage
Package Short Url https://bioconductor.org/packages/gage/
Package Downloads ReportDownload Stats