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This is the development version of crisprBase; for the stable release version, see crisprBase.

Base functions and classes for CRISPR gRNA design

Bioconductor version: Development (3.19)

Provides S4 classes for general nucleases, CRISPR nucleases, CRISPR nickases, and base editors.Several CRISPR-specific genome arithmetic functions are implemented to help extract genomic coordinates of spacer and protospacer sequences. Commonly-used CRISPR nuclease objects are provided that can be readily used in other packages. Both DNA- and RNA-targeting nucleases are supported.

Author: Jean-Philippe Fortin [aut, cre]

Maintainer: Jean-Philippe Fortin <fortin946 at gmail.com>

Citation (from within R, enter citation("crisprBase")):


To install this package, start R (version "4.4") and enter:

if (!require("BiocManager", quietly = TRUE))

# The following initializes usage of Bioc devel


For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:

Introduction to crisprBase HTML R Script
Reference Manual PDF


biocViews CRISPR, FunctionalGenomics, Software
Version 1.7.1
In Bioconductor since BioC 3.15 (R-4.2) (2 years)
License MIT + file LICENSE
Depends utils, methods, R (>= 4.1)
Imports BiocGenerics, Biostrings, GenomicRanges, graphics, IRanges, S4Vectors, stringr
System Requirements
URL https://github.com/crisprVerse/crisprBase
Bug Reports https://github.com/crisprVerse/crisprBase/issues
See More
Suggests BiocStyle, knitr, rmarkdown, testthat
Linking To
Depends On Me crisprDesign, crisprViz
Imports Me crisprBowtie, crisprBwa, crisprShiny, crisprVerse
Suggests Me
Links To Me
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package crisprBase_1.7.1.tar.gz
Windows Binary crisprBase_1.7.1.zip
macOS Binary (x86_64) crisprBase_1.7.1.tgz
macOS Binary (arm64) crisprBase_1.7.1.tgz
Source Repository git clone https://git.bioconductor.org/packages/crisprBase
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/crisprBase
Bioc Package Browser https://code.bioconductor.org/browse/crisprBase/
Package Short Url https://bioconductor.org/packages/crisprBase/
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