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clustSIGNAL

This is the development version of clustSIGNAL; for the stable release version, see clustSIGNAL.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21

ClustSIGNAL: a spatial clustering method


Bioconductor version: Development (3.24)

clustSIGNAL: clustering of Spatially Informed Gene expression with Neighbourhood Adapted Learning. A tool for adaptively smoothing and clustering gene expression data. clustSIGNAL uses entropy to measure heterogeneity of cell neighbourhoods and performs a weighted, adaptive smoothing, where homogeneous neighbourhoods are smoothed more and heterogeneous neighbourhoods are smoothed less. This not only overcomes data sparsity but also incorporates spatial context into the gene expression data. The resulting smoothed gene expression data is used for clustering and could be used for other downstream analyses.

Author: Pratibha Panwar [cre, aut, ctb] ORCID iD ORCID: 0000-0002-7437-7084 , Boyi Guo [aut], Haowen Zhao [aut], Stephanie Hicks [aut], Shila Ghazanfar [aut, ctb] ORCID iD ORCID: 0000-0001-7861-6997

Maintainer: Pratibha Panwar <pratibhapanwar.4 at gmail.com>

Citation (from within R, enter citation("clustSIGNAL")):

Pratibha Panwar, Boyi Guo, Haowen Zhao, Stephanie Hicks, Shila Ghazanfar. clustSIGNAL: ClustSIGNAL: a spatial clustering method. doi:10.18129/B9.bioc.clustSIGNAL, R package version 1.5.2, https://bioconductor.org/packages/clustSIGNAL.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("clustSIGNAL")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("clustSIGNAL")
ClustSIGNAL tutorial HTML R Script
Reference ManualPDF
NEWSText

Details

biocViews Clustering, GeneExpression, SingleCell, Software, Spatial, Transcriptomics
Version1.5.2
In Bioconductor sinceBioC 3.21 (R-4.5) (1.5 years)
License GPL-2
Depends R (>= 4.5.0), SpatialExperiment
Imports BiocParallel, BiocNeighbors, BiocSingular, bluster (>= 1.16.0), scater, harmony, SingleCellExperiment, SummarizedExperiment, methods, Matrix
System Requirements
URLhttps://sydneybiox.github.io/clustSIGNAL/
Bug Reportshttps://github.com/sydneybiox/clustSIGNAL/issues
See More
Suggests knitr, BiocStyle, testthat (>= 3.0.0), aricode, ggplot2, patchwork, dplyr, scattermore
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Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package clustSIGNAL_1.5.2.tar.gz
Windows Binary (x86_64) clustSIGNAL_1.5.2.zip
macOS Binary (big-sur-x86_64) clustSIGNAL_1.5.2.tgz
macOS Binary (sonoma-arm64) clustSIGNAL_1.5.2.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/clustSIGNAL
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/clustSIGNAL
Package Short Url https://bioconductor.org/packages/clustSIGNAL/
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