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cellscape

This is the development version of cellscape; for the stable release version, see cellscape.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14, 3.13, 3.12, 3.11, 3.10, 3.9, 3.8, 3.7, 3.6, 3.5

Explores single cell copy number profiles in the context of a single cell tree


Bioconductor version: Development (3.24)

CellScape facilitates interactive browsing of single cell clonal evolution datasets. The tool requires two main inputs: (i) the genomic content of each single cell in the form of either copy number segments or targeted mutation values, and (ii) a single cell phylogeny. Phylogenetic formats can vary from dendrogram-like phylogenies with leaf nodes to evolutionary model-derived phylogenies with observed or latent internal nodes. The CellScape phylogeny is flexibly input as a table of source-target edges to support arbitrary representations, where each node may or may not have associated genomic data. The output of CellScape is an interactive interface displaying a single cell phylogeny and a cell-by-locus genomic heatmap representing the mutation status in each cell for each locus.

Author: Shixiang Wang [aut, cre] ORCID iD ORCID: 0000-0001-9855-7357 , Maia Smith [aut]

Maintainer: Shixiang Wang <w_shixiang at 163.com>

Citation (from within R, enter citation("cellscape")):

Shixiang Wang, Maia Smith. cellscape: Explores single cell copy number profiles in the context of a single cell tree. doi:10.18129/B9.bioc.cellscape, R package version 1.37.0, https://bioconductor.org/packages/cellscape.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("cellscape")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("cellscape")
CellScape vignette HTML R Script
Reference ManualPDF

Details

biocViews Software, Visualization
Version1.37.0
In Bioconductor sinceBioC 3.5 (R-3.4) (9.5 years)
License GPL-3
Depends R (>= 3.3)
Imports dplyr (>= 0.4.3), gtools (>= 3.5.0), htmlwidgets (>= 0.5), jsonlite (>= 0.9.19), reshape2 (>= 1.4.1), stringr (>= 1.0.0)
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package cellscape_1.37.0.tar.gz
Windows Binary (x86_64) cellscape_1.37.0.zip
macOS Binary (big-sur-x86_64) cellscape_1.37.0.tgz
macOS Binary (sonoma-arm64) cellscape_1.37.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/cellscape
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/cellscape
Package Short Url https://bioconductor.org/packages/cellscape/
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