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VarCon

This is the development version of VarCon; for the stable release version, see VarCon.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14, 3.13

VarCon: an R package for retrieving neighboring nucleotides of an SNV


Bioconductor version: Development (3.24)

VarCon is an R package which converts the positional information from the annotation of an single nucleotide variation (SNV) (either referring to the coding sequence or the reference genomic sequence). It retrieves the genomic reference sequence around the position of the single nucleotide variation. To asses, whether the SNV could potentially influence binding of splicing regulatory proteins VarCon calcualtes the HEXplorer score as an estimation. Besides, VarCon additionally reports splice site strengths of splice sites within the retrieved genomic sequence and any changes due to the SNV.

Author: Johannes Ptok [aut, cre]

Maintainer: Johannes Ptok <Johannes.Ptok at posteo.de>

Citation (from within R, enter citation("VarCon")):

Johannes Ptok. VarCon: VarCon: an R package for retrieving neighboring nucleotides of an SNV. doi:10.18129/B9.bioc.VarCon, R package version 1.21.0, https://bioconductor.org/packages/VarCon.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("VarCon")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("VarCon")
Analysing SNVs with VarCon HTML R Script
Reference ManualPDF
NEWSText
LICENSEText

Details

biocViews AlternativeSplicing, FunctionalGenomics, Software
Version1.21.0
In Bioconductor sinceBioC 3.13 (R-4.1) (5.5 years)
License GPL-3
Depends Biostrings, BSgenome, GenomicRanges, R (>= 4.1)
Imports methods, stats, IRanges, shiny, shinycssloaders, shinyFiles, ggplot2
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package VarCon_1.21.0.tar.gz
Windows Binary (x86_64) VarCon_1.21.0.zip
macOS Binary (big-sur-x86_64) VarCon_1.21.0.tgz
macOS Binary (sonoma-arm64) VarCon_1.21.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/VarCon
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/VarCon
Package Short Url https://bioconductor.org/packages/VarCon/
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