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SpaceMarkers

This is the development version of SpaceMarkers; for the stable release version, see SpaceMarkers.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19

Spatial Interaction Markers


Bioconductor version: Development (3.24)

Spatial transcriptomic technologies have helped to resolve the connection between gene expression and the 2D orientation of tissues relative to each other. However, the limited single-cell resolution makes it difficult to highlight the most important molecular interactions in these tissues. SpaceMarkers, R/Bioconductor software, can help to find molecular interactions, by identifying genes associated with latent space interactions in spatial transcriptomics.

Author: Atul Deshpande [aut, cre] ORCID iD ORCID: 0000-0001-5144-6924 , Orian Stapleton [aut], Ludmila Danilova [ctb], Dmitrijs Lvovs [ctb] ORCID iD ORCID: 0009-0003-2152-6853

Maintainer: Atul Deshpande <adeshpande at jhu.edu>

Citation (from within R, enter citation("SpaceMarkers")):

Atul Deshpande, Orian Stapleton. SpaceMarkers: Spatial Interaction Markers. doi:10.18129/B9.bioc.SpaceMarkers, R package version 2.3.1, https://bioconductor.org/packages/SpaceMarkers.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("SpaceMarkers")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("SpaceMarkers")
Inferring Immune Interactions in Breast Cancer HTML R Script
SpaceMarkers with SpatialExperiment Objects HTML R Script
SpaceMarkers Functions Step-by-Step HTML R Script
Reference ManualPDF
NEWSText
LICENSEText

Details

biocViews GeneExpression, SingleCell, Software, Spatial, Transcriptomics
Version2.3.1
In Bioconductor sinceBioC 3.19 (R-4.4) (2.5 years)
License MIT + file LICENSE
Depends R (>= 4.4.0)
Imports SpatialExperiment, SingleCellExperiment, SummarizedExperiment, S4Vectors, matrixStats, matrixTests, rstatix, spatstat.explore, spatstat.geom, ape, hdf5r, nanoparquet, jsonlite, Matrix, qvalue, stats, utils, methods, ggplot2, reshape2, RColorBrewer, circlize, mixtools, dplyr, readbitmap, rlang, effsize, viridis
System Requirements
URLhttps://github.com/DeshpandeLab/SpaceMarkers
Bug Reportshttps://github.com/DeshpandeLab/SpaceMarkers/issues
See More
Suggests data.table, devtools, knitr, cowplot, rjson, rmarkdown, BiocStyle, BiocFileCache, testthat (>= 3.0.0), CoGAPS, ComplexHeatmap, zellkonverter, anndataR
Linking To
Enhances BiocParallel
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package SpaceMarkers_2.3.1.tar.gz
Windows Binary (x86_64) SpaceMarkers_2.3.1.zip (64-bit only)
macOS Binary (big-sur-x86_64) SpaceMarkers_2.3.1.tgz
macOS Binary (sonoma-arm64) SpaceMarkers_2.3.1.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/SpaceMarkers
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/SpaceMarkers
Package Short Url https://bioconductor.org/packages/SpaceMarkers/
Package Downloads ReportDownload Stats