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STRprofilerR

This is the development version of STRprofilerR; to use it, please install the devel version of Bioconductor.

Compare Short Tandem Repeat Profiles for Model Authentication


Bioconductor version: Development (3.24)

Compares short tandem repeat (STR) profiles to authenticate biomedical models such as cell lines and xenografts against the primary tissue samples they were derived from. Provides the Tanabe (Sorenson-Dice), Masters (versus query), and Masters (versus reference) similarity scores, heuristics for detecting sample mixing, flexible ingest of wide and long profile formats, comparison against user-supplied reference databases, and querying of the Cellosaurus knowledge base through the CLASTR REST API. A command line application is included for use in automated workflows, and a Shiny application for interactive queries.

Author: Jared Andrews [aut, cre] ORCID iD ORCID: 0000-0002-0780-6248

Maintainer: Jared Andrews <jared.andrews07 at gmail.com>

Citation (from within R, enter citation("STRprofilerR")):

Jared Andrews. STRprofilerR: Compare Short Tandem Repeat Profiles for Model Authentication. doi:10.18129/B9.bioc.STRprofilerR, R package version 0.99.1, https://bioconductor.org/packages/STRprofilerR.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("STRprofilerR")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("STRprofilerR")
Comparing STR profiles with STRprofilerR HTML R Script
Reference ManualPDF

Details

biocViews CellBasedAssays, Genetics, QualityControl, Software
Version0.99.1
In Bioconductor sinceBioC 3.24 (R-4.6)
License MIT + file LICENSE
Depends R (>= 4.5.0)
Imports httr2, IRanges, Matrix, methods, S4Vectors, stats, tools, utils
System Requirements
URLhttps://github.com/j-andrews7/STRprofilerR
Bug Reportshttps://github.com/j-andrews7/STRprofilerR/issues
See More
Suggests BiocStyle, bslib (>= 0.7.0), curl, DT, htmlwidgets, jsonlite, knitr, Rapp, readxl, rmarkdown, shiny (>= 1.8.1), SummarizedExperiment, testthat (>= 3.0.0), withr, writexl
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Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package STRprofilerR_0.99.1.tar.gz
Windows Binary (x86_64)
macOS Binary (big-sur-x86_64) STRprofilerR_0.99.1.tgz
macOS Binary (sonoma-arm64)
Source Repositorygit clone https://git.bioconductor.org/packages/STRprofilerR
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/STRprofilerR
Package Short Url https://bioconductor.org/packages/STRprofilerR/
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