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RadioGx

This is the development version of RadioGx; for the stable release version, see RadioGx.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14, 3.13, 3.12

Analysis of Large-Scale Radio-Genomic Data


Bioconductor version: Development (3.24)

Computational tool box for radio-genomic analysis which integrates radio-response data, radio-biological modelling and comprehensive cell line annotations for hundreds of cancer cell lines. The 'RadioSet' class enables creation and manipulation of standardized datasets including information about cancer cells lines, radio-response assays and dose-response indicators. Included methods allow fitting and plotting dose-response data using established radio-biological models along with quality control to validate results. Additional functions related to fitting and plotting dose response curves, quantifying statistical correlation and calculating area under the curve (AUC) or survival fraction (SF) are included. For more details please see the included documentation, references, as well as: Manem, V. et al (2018) <doi:10.1101/449793>.

Author: Venkata Manem [aut], Petr Smirnov [aut], Ian Smith [aut], Meghan Lambie [aut], Christopher Eeles [aut], Scott Bratman [aut], Jermiah Joseph [aut], Benjamin Haibe-Kains [aut, cre]

Maintainer: Benjamin Haibe-Kains <benjamin.haibe.kains at utoronto.ca>

Citation (from within R, enter citation("RadioGx")):

Venkata Manem, Petr Smirnov, Ian Smith, Meghan Lambie, Christopher Eeles, Scott Bratman, Jermiah Joseph, Benjamin Haibe-Kains. RadioGx: Analysis of Large-Scale Radio-Genomic Data. doi:10.18129/B9.bioc.RadioGx, R package version 2.17.0, https://bioconductor.org/packages/RadioGx.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("RadioGx")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("RadioGx")
RadioGx: An R Package for Analysis of Large Radiogenomic Datasets HTML R Script
Reference ManualPDF
NEWSText

Details

biocViews Classification, Pharmacogenetics, Pharmacogenomics, QualityControl, Software, Survival
Version2.17.0
In Bioconductor sinceBioC 3.12 (R-4.0) (6 years)
License GPL-3
Depends R (>= 4.1), CoreGx
Imports SummarizedExperiment, BiocGenerics, data.table, S4Vectors, Biobase, parallel, BiocParallel, RColorBrewer, caTools, magicaxis, methods, reshape2, scales, grDevices, graphics, stats, utils, assertthat, matrixStats, downloader
System Requirements
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Suggests rmarkdown, BiocStyle, knitr, pander, markdown
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Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package RadioGx_2.17.0.tar.gz
Windows Binary (x86_64) RadioGx_2.17.0.zip (64-bit only)
macOS Binary (big-sur-x86_64) RadioGx_2.17.0.tgz
macOS Binary (sonoma-arm64) RadioGx_2.17.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/RadioGx
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/RadioGx
Package Short Url https://bioconductor.org/packages/RadioGx/
Package Downloads ReportDownload Stats