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PolySTest

This is the development version of PolySTest; for the stable release version, see PolySTest.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20

PolySTest: Detection of differentially regulated features. Combined statistical testing for data with few replicates and missing values


Bioconductor version: Development (3.24)

The complexity of high-throughput quantitative omics experiments often leads to low replicates numbers and many missing values. We implemented a new test to simultaneously consider missing values and quantitative changes, which we combined with well-performing statistical tests for high confidence detection of differentially regulated features. The package contains functions to run the test and to visualize the results.

Author: Veit Schwämmle [aut, cre] ORCID iD ORCID: 0000-0002-9708-6722

Maintainer: Veit Schwämmle <veits at bmb.sdu.dk>

Citation (from within R, enter citation("PolySTest")):

Veit Schwämmle. PolySTest: PolySTest: Detection of differentially regulated features. Combined statistical testing for data with few replicates and missing values. doi:10.18129/B9.bioc.PolySTest, R package version 1.7.0, https://bioconductor.org/packages/PolySTest.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("PolySTest")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("PolySTest")
PolySTest HTML R Script
Reference ManualPDF
NEWSText
LICENSEText

Details

biocViews DifferentialExpression, MassSpectrometry, Proteomics, Software
Version1.7.0
In Bioconductor sinceBioC 3.20 (R-4.4) (2 years)
License GPL-2
Depends R (>= 4.4.0)
Imports fdrtool (>= 1.2.15), limma (>= 3.61.3), matrixStats (>= 0.57.0), qvalue (>= 2.22.0), shiny (>= 1.5.0), SummarizedExperiment (>= 1.20.0), knitr (>= 1.33), plotly (>= 4.9.4), heatmaply (>= 1.1.1), circlize (>= 0.4.12), UpSetR (>= 1.4.0), gplots (>= 3.1.1), S4Vectors (>= 0.30.0), parallel (>= 4.1.0), grDevices (>= 4.1.0), graphics (>= 4.1.0), stats (>= 4.1.0), utils (>= 4.1.0)
System Requirements
URLhttps://github.com/computproteomics/PolySTest
Bug Reportshttps://github.com/computproteomics/PolySTest/issues
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package PolySTest_1.7.0.tar.gz
Windows Binary (x86_64) PolySTest_1.7.0.zip
macOS Binary (big-sur-x86_64) PolySTest_1.7.0.tgz
macOS Binary (sonoma-arm64) PolySTest_1.7.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/PolySTest
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/PolySTest
Package Short Url https://bioconductor.org/packages/PolySTest/
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