Bioconductor Developer Survey 2026 Now Open!

MSstats

This is the development version of MSstats; for the stable release version, see MSstats.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14, 3.13, 3.12, 3.11, 3.10, 3.9, 3.8, 3.7, 3.6, 3.5, 3.4, 3.3, 3.2, 3.1, 3.0, 2.14, 2.13

Protein Significance Analysis in DDA, SRM and DIA for Label-free or Label-based Proteomics Experiments


Bioconductor version: Development (3.24)

A set of tools for statistical relative protein significance analysis in DDA, SRM and DIA experiments.

Author: Meena Choi [aut, cre], Mateusz Staniak [aut], Devon Kohler [aut], Tony Wu [aut], Deril Raju [aut], Tsung-Heng Tsai [aut], Ting Huang [aut], Olga Vitek [aut]

Maintainer: Meena Choi <mnchoi67 at gmail.com>

Citation (from within R, enter citation("MSstats")):

Meena Choi, Mateusz Staniak, Devon Kohler, Tony Wu, Deril Raju, Tsung-Heng Tsai, Ting Huang, Olga Vitek. MSstats: Protein Significance Analysis in DDA, SRM and DIA for Label-free or Label-based Proteomics Experiments. doi:10.18129/B9.bioc.MSstats, R package version 4.21.1, https://bioconductor.org/packages/MSstats.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("MSstats")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("MSstats")
MSstats: Protein/Peptide significance analysis HTML R Script
MSstats: Metabolomics workflow with MZMine HTML R Script
MSstats+: Peak quality-weighted differential analysis HTML R Script
MSstats: End to End Workflow HTML R Script
Reference ManualPDF
LICENSEText

Details

biocViews ImmunoOncology, MassSpectrometry, Normalization, Proteomics, QualityControl, Software, TimeCourse
Version4.21.1
In Bioconductor sinceBioC 2.13 (R-3.0) (13 years)
License Artistic-2.0
Depends R (>= 4.0)
Imports MSstatsConvert, data.table, checkmate, MASS, htmltools, limma, lme4, preprocessCore, survival, utils, Rcpp, ggplot2 (>= 3.4.0), ggrepel, gplots, plotly, marray, stats, grDevices, graphics, methods, statmod, parallel, rlang
System Requirements
URLhttp://msstats.org
Bug Reportshttps://groups.google.com/forum/#!forum/msstats
See More
Suggests BiocStyle, knitr, rmarkdown, tinytest, covr, markdown, mockery, kableExtra
Linking To Rcpp, RcppArmadillo
Enhances
Depends On Me MSstatsBioNet
Imports Me artMS, MSstatsBig, MSstatsLiP, MSstatsPTM, MSstatsShiny, MSstatsTMT
Suggests Me MSstatsResponse
Links To Me
Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package MSstats_4.21.1.tar.gz
Windows Binary (x86_64) MSstats_4.21.1.zip
macOS Binary (big-sur-x86_64) MSstats_4.21.1.tgz
macOS Binary (sonoma-arm64) MSstats_4.21.1.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/MSstats
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/MSstats
Package Short Url https://bioconductor.org/packages/MSstats/
Package Downloads ReportDownload Stats